The Diabetic Kidney

  • Pedro Cortes
  • Carl Erik Mogensen
Part of the Contemporary Diabetes book series (CDI)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Basic Pathophysiology and Biochemistry of Diabetic Nephropathy

    1. Front Matter
      Pages 1-1
    2. Pathophysiology

      1. David J. Leehey, Ashok K. Singh, Rekha Singh
        Pages 3-21
      2. Pamela K. Carmines, Joseph P. Bast, Naohito Ishii
        Pages 23-36
    3. Interstitial Disease

    4. Podocytes

      1. George Jerums, Sianna Panagiotopoulos, Richard MacIsaac
        Pages 59-77
    5. Altered Metabolic Pathways

      1. Balakuntalam S. Kasinath, Myung Ja Lee, Denis Feliers, Nahum Sonenberg
        Pages 97-116
      2. I. George Fantus, Howard J. Goldberg, Catharine I. Whiteside, Delilah Topic
        Pages 117-133
    6. Nonenzymatic Glycosylation

      1. Vivette D’Agati, Ann Marie Schmidt
        Pages 137-148
    7. Oxidative Stress

      1. Frederick R. DeRubertis, Patricia A. Cravens
        Pages 151-172
    8. Growth Factors

    9. New Approaches to the Study of Diabetic Nephropathy

      1. Shinya Mizuno, Toshikazu Nakamura
        Pages 225-253
      2. Visith Thongboonkerd
        Pages 255-275
      3. Katalin Susztak, Erwin Bottinger, Kumar Sharma
        Pages 277-288
      4. Keiji Isshiki, Daisuke Koya, Masakazu Haneda
        Pages 289-304
      5. Jerry Yee, Balazs Szamosfalvi
        Pages 305-313
      6. Keith A. Hruska, Laura Petris, Tingting Li, Song Wang, Theresa Geurs, Frank Strebeck et al.
        Pages 315-326

About this book

Introduction

Although diabetic kidney disease is the most prevalent cause of end-stage renal disease and the disease most often leading to chronic renal replacement therapy and kidney transplantation, there has been, in recent years, a steady increase in basic and clinical knowledge of the problem. In The Diabetic Kidney, a stellar group of international researchers and clinicians joins forces to independently survey recent findings, ideas, and hypotheses about the causes and treatment of diabetic nephropathy. Drawing on many years of experience, the authors cover both the basic pathogenic mechanisms of the disease, as well as many of its clinical aspects of identification, management, and new therapeutic approaches. Not always in total agreement, their views reflect the present state of knowledge and its uncertainties, and offer a composite of different authoritative views on the causes of diabetic kidney disease. Highlights include an entire section devoted to novel approaches to studying diabetic nephropathy with the most advanced molecular techniques, and comprehensive descriptions of the most up-to-date views on the diagnosis and treatment of the disease.
State of the art and illuminating, The Diabetic Kidney offers both researchers and practicing clinicians a clear understanding of the progress that has been made regarding the pathogenesis of diabetic nephropathy and of the therapeutic interventions needed to prevent its development or treat it.

Keywords

Diabetes biosynthesis growth growth factor kidney protein signal transduction

Editors and affiliations

  • Pedro Cortes
    • 1
  • Carl Erik Mogensen
    • 2
  1. 1.Division of Nephrology and HypertensionDepartment of Medicine, Henry Ford HospitalDetroit
  2. 2.Department of Internal Medicine M (Diabetes and Endocrinology)Aarhus University HospitalAarhusDenmark

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-59745-153-6
  • Copyright Information Humana Press Inc. 2006
  • Publisher Name Humana Press
  • eBook Packages Medicine
  • Print ISBN 978-1-58829-624-5
  • Online ISBN 978-1-59745-153-6
  • About this book