Table of contents

  1. Front Matter
    Pages i-xiv
  2. Polyamines in Signal Transduction of Cell Proliferation

    1. Front Matter
      Pages 1-1
    2. Patrick M. Woster
      Pages 3-24
    3. Cheryl A. Hobbs, Susan K. Gilmour
      Pages 75-89
    4. Sripriya Venkiteswaran, Thresia Thomas, T. J. Thomas
      Pages 91-122
    5. Lisa M. Shantz, Emanuele Giordano
      Pages 123-137
    6. Raymond G. Schipper, Vincent Cuijpers, Johannes C. Romijn, Albert A. J. Verhofstad
      Pages 155-168
    7. Joseph Satriano
      Pages 169-186
    8. Jack W. Olson, Mark N. Gillespie
      Pages 187-202
  3. Polyamines in Cellular Signaling of Apoptosis, Carcinogenesis, and Cancer Therapy

    1. Front Matter
      Pages 203-203
    2. Robert A. Casero Jr., Alison V. Fraser, Tracy Murray-Stewart, Amy Hacker, Naveen Babbar, Jennifer Fleischer et al.
      Pages 205-232
    3. Jonas A. Nilsson, John L. Cleveland
      Pages 249-266
    4. Heather M. Wallace, Alun Hughes
      Pages 267-278
    5. Rupesh Chaturvedi, Keith T. Wilson
      Pages 293-312

About this book

Introduction

Polyamine Cell Signaling: Physiology, Pharmacology, and Cancer Research presents current state-of-the-art findings relevant to cellular and molecular functions of polyamines, as well as providing the underlying conceptual basis and knowledge regarding potential therapeutic-targeting polyamines and polyamine metabolism leading to the development of new therapeutic approaches for cancers and other diseases. Divided into four main parts that include polyamines in signal transduction of cell proliferation; polyamines in cellular signaling of apoptosis, carcinogenesis, and cancer therapy; polyamines in cell motility and cell-cell interactions; and polyamine homeostasis and transport, these topics are addressed by internationally recognized experts in their respective fields.
This timely guide provides the whole picture of polyamines-past, present, and potential future, and offers a wealth of information regarding basic knowledge and current progress on cellular functions of polyamines and their potential clinical applications in cancer therapy. For investigators in the fields of polyamines, physiology, pharmacology, and cancer research, Polyamine Cell Signaling: Physiology, Pharmacology, and Cancer Research serves as a foundation based on research and addresses the potential for subsequent applications in clinical practice.

Keywords

DNA apoptosis biological functions influence physiology regulation signal transduction tumorigenesis

Editors and affiliations

  • Jian-Ying Wang
    • 1
  • Robert A. CaseroJr.
    • 2
  1. 1.Departments of Surgery and PathologyUniversity of Maryland School of Medicine and Baltimore Veterans Affairs Medical CenterBaltimore
  2. 2.The Sidney Kimmel Comprehensive Cancer CenterJohns Hopkins University School of MedicineBaltimore

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-59745-145-1
  • Copyright Information Humana Press Inc. 2006
  • Publisher Name Humana Press
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-58829-625-2
  • Online ISBN 978-1-59745-145-1
  • About this book