Essentials of Restenosis

For the Interventional Cardiologist

  • Henricus J. Duckers
  • Elizabeth G. Nabel
  • Patrick W. Serruys

Part of the Contemporary Cardiology book series (CONCARD)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Pathophysiology and Diagnosis

    1. Front Matter
      Pages 1-1
    2. Henricus J. Duckers, Caroline Cheng, Dennie Tempel, Patrick W. Serruys
      Pages 3-5
    3. Randolph L. Geary, Alexander W. Clowes
      Pages 7-28
    4. Ganesh Manoharan, Giedrius Davidavicius, William Wijns
      Pages 29-46
    5. Renu Virmani, Frank D. Kolodgie, Aloke V. Finn, Herman K. Gold
      Pages 47-58
    6. Attila Thury, Jolanda J. Wentzel, Frank J. H. Gijsen, Johan C. H. Schuurbiers, Rob Krams, Pim J. de Feyter et al.
      Pages 59-83
    7. Arturo G. Touchard, Robert S. Schwartz
      Pages 131-150
  3. Genetic Basis of Restenosis

    1. Front Matter
      Pages 151-151
    2. Thomas W. Johnson, Karl R. Karsch
      Pages 153-165
    3. Dietlind Zohlnhöfer, Franz-Josef Neumann
      Pages 167-173
    4. Santhi K. Ganesh, Elizabeth G. Nabel
      Pages 175-183
    5. Andrew Wragg, Manfred Boehm
      Pages 199-212
    6. Gerard Pasterkamp, Bradley H. Strauss, Dominique de Kleijn
      Pages 213-225
    7. Alexey Kuroedov, Francesco Cosentino, Felix C. Tanner, F. Lüscher
      Pages 227-243
  4. Diagnosis of Restenosis

    1. Front Matter
      Pages 245-245
    2. Volker Klauss, Nico H. J. Pijls
      Pages 247-256
    3. Giedrius Davidavicius, Ganesh Manoharan, William Wijns
      Pages 257-275
    4. Robert Jan M. van Geuns, Timo Baks
      Pages 277-285
  5. Therapy of Restenosis

    1. Front Matter
      Pages 299-299
    2. Pim J. de Feyter, Georgios Sianos
      Pages 301-306
    3. Ron Waksman
      Pages 307-332
    4. Antonio Colombo, Alaide Chieffo
      Pages 333-352
    5. Marco A. Costa, Alexandre Abizaid, Amanda G. M. R. Sousa, J. Eduardo Sousa
      Pages 353-367
    6. Takafumi Tsuji, Hideo Tamai, Keiji Igaki
      Pages 369-375
  6. Biotechnology in the Treatment of Restenosis

    1. Front Matter
      Pages 377-377
    2. Gurpreet S. Sandhu, Robert D. Simari
      Pages 379-394
    3. Nicholas Kipshidze, Mykola Tsapenko, George Dangas, Pat Iversen
      Pages 395-406
    4. Ravish Sachar, Eric J. Topol
      Pages 419-442
  7. Back Matter
    Pages 443-458

About this book


Essentials of Restenosis provides the practicing cardiologists and biologists an elaborate review of the current advances in the field. Authors explore the process of restenosis from bench to bedside, encompassing in equal detail the newest scientific findings of the biological mechanisms as well as the progression in development of diagnostics and treatments. The volume also provides the reader with a basic understanding of the biological process and the latest diagnostics and treatments of the disease, with an up-to-date detailed discussion of the most important recent findings.

Leading interventional cardiologists, including Patrick Serruys, Eric Topol, David Holmes, Thomas Luscher and others provide the gold-standard reference on the treatment of restenosis (coronary artery blockage) for interventional cardiologists. Dr. Serruys, who pioneered the use of drug-eluting stents, and other pioneers in the field cover everything from non-invasive imaging, to eluting stents, to brachytherapy through to the latest molecular biology-based treatments including antisense, stem cells and gene therapy, making this an essential reference for all interventional cardiologists. Thorough chapters discuss the current understanding on the pathophysiology, molecular and genetic base, and methods of diagnosis of restenosis, and present the current state-of-the-art management, including pharmacotherapy and interventional percutaneous approaches using brachytherapy, gene therapy and drug eluting stent technology.

All this makes Essentials of Restenosis an excellent handbook for introducing new intervention cardiologists, vascular biologists, and medical students into the subject. This text provides the reader with a complete overview of the basic and applied knowledge of restenosis, leading to better insight and decision-making in clinical practice.


Stent anatomy computed tomography (CT) coronary imaging diagnosis diagnostics gene therapy immune system magnetic resonance magnetic resonance imaging magnetic resonance imaging (MRI) pathophysiology physiology tomography vascular disease

Editors and affiliations

  • Henricus J. Duckers
    • 1
  • Elizabeth G. Nabel
    • 2
  • Patrick W. Serruys
    • 1
  1. 1.Thoraxcenter, Erasmus Medical Center RotterdamRotterdamThe Netherlands
  2. 2.The Nabel Lab, Genome Technology Branch, NHGRI Division of Intramural Research, National Heart, Lung, and Blood InstituteNational Institutes of HealthBethesda

Bibliographic information