Angiogenesis and Direct Myocardial Revascularization

  • Roger J. Laham
  • Donald S. Baim

Part of the Contemporary Cardiology book series (CONCARD)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Roger J. Laham, Donald S. Baim
    Pages 1-17
  3. Peter Oettgen
    Pages 19-36
  4. Aysegul Yegin, Nicolas A. Chronos
    Pages 37-64
  5. Pierre Voisine, Joanna J. Wykrzykowska, Munir Boodhwani, David G. Harrison, Roger J. Laham, Frank W. Sellke
    Pages 65-105
  6. Erik T. Price, Alan C. Yeung, Mehrdad Rezaee
    Pages 107-141
  7. Justin D. Pearlman
    Pages 143-184
  8. Kwang Soo Cha, Robert S. Schwartz, Timothy D. Henry
    Pages 185-214
  9. Pinak B. Shah, Kapildeo Lotun, Douglas W. Losordo
    Pages 215-244
  10. Richard E. Waters, Brian H. Annex
    Pages 245-259
  11. Yong-Fu Xiao, Jiang-Yong Min, James P. Morgan
    Pages 283-310
  12. Audrey Rosinberg, Jamal S. Rana, Roger J. Laham
    Pages 311-328
  13. Keith A. Horvath
    Pages 329-348
  14. Back Matter
    Pages 349-357

About this book


Despite the rapid progress in surgical and catheter-based revascularization, an alternative treatment strategy is needed for the ever-increasing number of patients who are either not candidates for these therapies or remain symptomatic after revascularization and maximal ongoing medical treatment. In Angiogenesis and Direct Myocardial Revascularization, an interdisciplinary panel of pioneers and opinion leaders review the basic, preclinical, clinical, and developmental pathways to new treatment strategies, such as therapeutic angiogenesis and myogenesis. In their assessments, the authors take advantage of new biological understanding, novel therapeutic targets, multiple available and well-studied therapeutic strategies, and the necessary imaging techniques to measure outcomes. Their in-depth discussions cover the identification of new therapeutic targets and pathways, the investigation of transcriptional factors, master switch molecules, cell-based approaches, chemokines, a better understanding of the effects of aging, endothelial dysfunction, and hypercholesterolemia in response to angiogenic stimuli. Highlights include examination of drug delivery problems, outcomes measure, stem therapy, high-risk interventions, development pathways, and future possibilities.
Authoritative and state-of-the-art, Angiogenesis and Direct Myocardial Revascularization provides all internists, cardiologists, vascular disease specialists, scientists, and industry with a highly effective scientific and clinical basis for helping patients with end-stage ischemic heart disease, peripheral vascular disease, and congestive heart failure.


Chemokine angiogenesis cardiovascular circulation drug drug delivery gene therapy transplantation

Editors and affiliations

  • Roger J. Laham
    • 1
  • Donald S. Baim
    • 2
  1. 1.Beth Israel Deaconess Medical CenterBoston
  2. 2.Brigham and Women’s HospitalBoston

Bibliographic information