Male Hypogonadism

Basic, Clinical, and Therapeutic Principles

  • Stephen J. Winters

Part of the Contemporary Endocrinology book series (COE)

Table of contents

  1. Front Matter
    Pages i-x
  2. Stephen J. Winters, Alan C. Dalkin
    Pages 1-21
  3. Qiang Dong, Matthew P. Hardy
    Pages 23-43
  4. Leo Dunkel
    Pages 63-79
  5. William F. Crowley, Nelly Pitteloud
    Pages 81-100
  6. Barto J. Otten, Nike M. M. L. Stikkelbroeck, Ad R. M. M. Hermus
    Pages 125-137
  7. Annamaria Colao, Giovanni Vitale, Michele De Rosa, Gaetano Lombardi
    Pages 139-158
  8. John K. Amory, William J. Bremner
    Pages 159-169
  9. Peter A. Lee, Barry A. Kogan, Michael T. Coughlin
    Pages 171-206
  10. Shalender Bhasin
    Pages 207-225
  11. Peter Y. Liu, David J. Handelsman
    Pages 227-245
  12. Simon J. Howell, Stephen M. Shalet
    Pages 247-262
  13. Johannes D. Veldhuis, Ali Iranmanesh, Daniel Keenan
    Pages 263-286
  14. Richard M. Sharpe
    Pages 287-304
  15. Anthony C. Hackney, Jennifer Dobridge
    Pages 305-329
  16. Joseph M. Zmuda, Stephen J. Winters
    Pages 331-351
  17. Christina Wang, Ronald S. Swerdloff
    Pages 353-369
  18. Marion Depenbusch, Eberhard Nieschlag
    Pages 371-386
  19. Back Matter
    Pages 387-396

About this book


Recent advances in cellular and molecular biology have substantially increased our understanding of normal and abnormal hypothalamic-pituitary-testicular function. In Male Hypogonadism: Basic, Clinical, and Therapeutic Principles, well-known clinicians and basic scientists comprehensively explain and apply these new insights to the treatment of hypogonadal men. The authors focus on the specific causes of gonadotropin deficiency and testicular failure arising from disorders of the brain and the testis and from gene defects and chronic illness. Additional chapters describe the endocrine mechanism for the decline of testicular function with aging, summarize the data supporting the negative impact of environmental toxins on testicular function, and discuss the testicular consequences of exercise and obesity. Also included is an overview of androgen replacement therapy and a chapter devoted to current approaches to stimulating spermatogenesis in gonadotropin-deficient men.
Comprehensive and highly practical, Male Hypogonadism: Basic, Clinical, and Therapeutic Principles lucidly interprets a large body of scientific information on male reproductive endocrinology to provide a thorough understanding of the pathophysiology, clinical characteristics, and treatments for disorders that adversely affect testicular function.


Gonadotropin cancer endocrinology pathophysiology puberty spermatogenesis testis

Editors and affiliations

  • Stephen J. Winters
    • 1
  1. 1.Division of Endocrinology, Metabolism and Diabetes, Department of MedicineUniversity of LouisvilleLouisvilleUSA

Bibliographic information