Human Embryonic Stem Cells

  • Arlene Y. Chiu
  • Mahendra S. Rao

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Policy

  3. Types of Pluripotent Cells

    1. Front Matter
      Pages 61-61
    2. Jonathan S. Draper, Harry Moore, Peter W. Andrews
      Pages 63-87
    3. Felipe Prosper, Catherine M. Verfaillie
      Pages 89-111
    4. Melissa K. Carpenter, Chunhui Xu, Christine A. Daigh, Jessica E. Antosiewicz, James A. Thomson
      Pages 113-126
    5. Michal Amit, Hanna Segev, Dorit Manor, Joseph Itskovitz-Eldor
      Pages 127-141
  4. Differentiation

    1. Front Matter
      Pages 143-143
    2. Chunhui Xu, Melissa K. Carpenter
      Pages 181-199
    3. Sharon Gerecht-Nir, Joseph Itskovitz-Eldor
      Pages 201-217
  5. Therapeutics

    1. Front Matter
      Pages 237-237
    2. Calvin B. Harley, Mahendra S. Rao
      Pages 239-264
    3. Micha Drukker, Nissim Benvenisty
      Pages 265-284
    4. Jose B. Cibelli
      Pages 285-295
    5. Alexander Kamb, Mani Ramaswami, Mahendra S. Rao
      Pages 297-322
    6. Paul J. Reier, John Q. Trojanowski, Virginia M-Y. Lee, Margaret J. Velardo
      Pages 345-387
  6. Back Matter
    Pages 389-461

About this book


Although there is great interest in the potential for using stem cells as cell replacements and other treatments for diseases that currently have no cure, research on the biology of human embryonic stem cells is still in its infancy. In Human Embryonic Stem Cells, pioneers, leaders, and experts in this emerging field join forces to address all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, these topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. The authors cover the criteria used by investigators in different fields to recognize mature phenotypes of specific tissues. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.
Reviewing the most pressing issues involved in human embryonic stem cell research, Human Embryonic Stem Cells, provides an invaluable sourcebook for researchers seeking a review of their basic biology and an unbiased assessment of their potential for new therapies.


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Editors and affiliations

  • Arlene Y. Chiu
    • 1
  • Mahendra S. Rao
    • 2
  1. 1.National Institute of Neurological Disorders and StrokeNational Institutes of HealthBethesdaUSA
  2. 2.National Institute on AgingNational Institutes of HealthBaltimoreUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2003
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-61737-484-5
  • Online ISBN 978-1-59259-423-8
  • Buy this book on publisher's site