Handbook of Proteomic Methods

  • P. Michael Conn

Table of contents

  1. Front Matter
    Pages i-xiv
  2. General Techniques

    1. Front Matter
      Pages 1-1
    2. Paul R. Graves, Timothy A. J. Haystead
      Pages 3-16
    3. Nathalie Norais, Renzo Nogarotto, Emilia Tiziana Iacobini, Ignazio Garaguso, Renata Grifantini, Giuliano Galli et al.
      Pages 17-28
    4. Shanhua Lin, Ning Tang, Scot R. Weinberger
      Pages 59-72
    5. Karen J. Martin, Wayne F. Patton
      Pages 93-105
    6. Birte Schulenberg, Wayne F. Patton
      Pages 107-115
    7. Alexandra Huhalov, Daniel I. R. Spencer, Kerry A. Chester
      Pages 117-127
    8. Ian I. Stewart, Ty Thomson, Daniel Figeys, Henry S. Duewel
      Pages 145-179
    9. Bart Devreese, Frank Vanrobaeys, Elke Lecocq, Joél Smet, Rudy Van Coster, Jozef Van Beeumen
      Pages 181-191
    10. Joel R. Bock, David A. Gough
      Pages 193-222
  3. Post-Translational Modifications, Variants, and Isoforms

    1. Front Matter
      Pages 223-223
    2. Catherine A. Cooper, Elisabeth Gasteiger, Nicolle H. Packer
      Pages 225-231
    3. Catherine A. Cooper, Hiren J. Joshi, Mathew J. Harrison, Marc R. Wilkins, Nicolle H. Packer
      Pages 233-239
    4. Li-Rong Yu, Van M. Hoang, Timothy D. Veenstra
      Pages 241-257
    5. Frédéric Nikitin, Frédérique Lisacek
      Pages 259-268
    6. Michael Weitzhandler, Dell Farnan, Nebojsa Avdalovic, Chris Pohl
      Pages 269-280
  4. Specific Systems

    1. Front Matter
      Pages 281-281
    2. Gary D. Luker, Vijay Sharma, David Piwnica-Worms
      Pages 283-298
    3. Eric T. Fung
      Pages 299-307
    4. Vladimir Knezevic, Michael R. Emmert-Buck
      Pages 309-317
    5. Paola Perego, Giovanni Luca Beretta, Laura Gatti
      Pages 319-330
    6. Terence C. W. Poon, Philip J. Johnson
      Pages 331-345
    7. Sheng-He Huang, Ambrose Jong, James T. Summersgill
      Pages 347-356
    8. Haike Antelmann, Jan Maarten van Dijl, Michael Hecker
      Pages 357-374
    9. Visith Thongboonkerd, Elias Klein, Jon B. Klein
      Pages 375-395
    10. Jan W. A. Smit, Johannes A. Romijn
      Pages 397-408
    11. Christina Mihr, Hans-Peter Braun
      Pages 409-416
  5. Data Analysis

    1. Front Matter
      Pages 417-417
    2. Mauno Vihinen
      Pages 419-428
    3. Andreas Schlosser, Wolf D. Lehmann
      Pages 463-472
    4. Ralf Mrowka, Hanspeter Herzel
      Pages 473-476
    5. Robin Gras, Patricia Hernandez, Markus Müller, Ron D. Appel
      Pages 477-485
  6. Back Matter
    Pages 487-510

About this book


The developing new field of proteomics holds significant promise for a deeper understanding of complicated biological systems, as well as for novel approaches to the cure of disease. In the Handbook of Proteomic Methods, P. Michael Conn has assembled a panel of well-recognized experts to describe a wide range of powerful techniques for identifying and analyzing the diversity of proteins expressed in cells. These readily reproducible proteomic methods range from general to specific techniques, and include methods for data analysis, post-translational modification, and its variants and isoforms. Additional methods demonstrate the application of proteomics to the discovery of serological tumor markers, to identifying the determinants of sensitivity to antitumor drugs, and to specialized fields, such as endocrinology, plant biology, nephrology, and urology. Each fully tested protocol is described in step-by-step detail, complete with tricks of the trade and hints on avoiding pitfalls. The detail of description exceeds that usually found in primary publications.
Wide-ranging and practical, the Handbook of Proteomic Methods offers scientists entering, or already active in, the field a fully referenced compendium of easy-to-use proteomic methods-each reflecting the power and promise of proteomics in illuminating complex biological systems and in promoting the development of novel drugs for the amelioration of disease.


Amino acid Proteomics proteins transcription translation

Editors and affiliations

  • P. Michael Conn
    • 1
  1. 1.Oregon National Primate Research CenterOregon Health and Science UniversityBeavertonUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2003
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-61737-504-0
  • Online ISBN 978-1-59259-414-6
  • Buy this book on publisher's site