Chronic Lymphocytic Leukemia

Molecular Genetics, Biology, Diagnosis, and Management

  • Guy B. Faguet

Part of the Contemporary Hematology book series (CH)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Gerald E. Marti, Vincent Zenger
      Pages 3-54
  3. Biology and Genetics

    1. Front Matter
      Pages 55-55
    2. Stephan Stilgenbauer, Peter Lichter, Hartmut Döhner
      Pages 57-75
    3. Terry Hamblin
      Pages 95-107
    4. Patrick B. Johnston, Neil E. Kay
      Pages 109-121
    5. Enrica Orsini, Robin Foa
      Pages 123-142
  4. Clinical Aspects: Diagnosis

    1. Front Matter
      Pages 143-143
    2. Vonda K. Douglas, Raul C. Braylan
      Pages 145-161
    3. Gunnar Juliusson
      Pages 163-171
    4. Alberto Orfao, Julia Almeida, Maria Luz Sanchez, Jesus F. San Miguel
      Pages 173-190
  5. Clinical Aspects: Prognosis

    1. Front Matter
      Pages 191-191
    2. Kanti R. Rai, Niraj Gupta
      Pages 193-199
    3. Francesc Bosch, Emili Montserrat
      Pages 201-215
  6. Clinical Aspects: Treatment

    1. Front Matter
      Pages 217-217
    2. Guillaume Dighiero
      Pages 219-240
    3. Alessandra Ferrajoli, Michael J. Keating, Susan M. O’Brien
      Pages 241-254
    4. Thomas S. Lin, Margaret S. Lucas, John C. Byrd
      Pages 269-298
    5. Arthur E. Frankel, Robert J. Kreitman
      Pages 299-314
    6. Upendra P. Hegde, Wyndham H. Wilson
      Pages 315-328
    7. Januario E. Castro, Thomas J. Kipps
      Pages 329-340
  7. Clinical Aspects: Complications

    1. Front Matter
      Pages 341-341
    2. Gerald P. Bodey, Dimitrios Kontoyiannis, Michael J. Keating
      Pages 343-359
    3. Terry Hamblin
      Pages 361-376
  8. Familial and Juvenile Chronic Lymphocytic Leukemia

    1. Front Matter
      Pages 387-387
    2. Martin R. Yuille, Daniel Catovsky, Richard S. Houlston
      Pages 389-400
    3. Francesca R. Mauro, Robin Foa
      Pages 401-413
  9. Back Matter
    Pages 415-421

About this book


Chronic lymphocytic leukemia (CLL) is the second most frequently encountered leukemia in North America and Europe, and the object of considerable research and treatment. In Chronic Lymphocytic Leukemia: Molecular Genetics, Biology, Diagnosis, and Management, prominent physicians and researchers from the leading medical centers in the United States and Europe critically review the latest scientific advances in our understanding of the molecular genetics and biology of CLL and apply them to its best management. Their comprehensive reviews of the clinical aspects of CLL focus on diagnosis, prognosis, multifaceted treatment options, and complications. Among the diverse treatments considered are chemotherapy, autologous and allogeneic transplantations, monoclonal antibody therapy, immunotoxin therapy, gene therapy, and several promising new therapeutic strategies. Familial and juvenile chronic lymphocytic leukemia are also discussed.
Cutting-edge and clinically focused, Chronic Lymphocytic Leukemia: Molecular Genetics, Biology, Diagnosis, and Management offers today's hematologists and oncologists the opportunity to update their clinical knowledge and sort out the range of available therapies to provide optimal patient care.


Staging antibody cell chemotherapy cytokine cytokines evolution gene therapy genes genetics leukemia molecular biology molecular genetics pathogenesis transplantation

Editors and affiliations

  • Guy B. Faguet
    • 1
  1. 1.Section of Hematology/OncologyVeterans Affairs Medical CenterAugustaUSA

Bibliographic information