Practical Immunopathology of the Skin

  • Bruce R. Smoller

Part of the Current Clinical Pathology book series (CCPATH)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Bruce R. Smoller
      Pages 3-7
    3. Bruce R. Smoller
      Pages 9-28
  3. Antibody Directory

    1. Front Matter
      Pages 29-29
    2. Bruce R. Smoller
      Pages 31-51
    3. Bruce R. Smoller
      Pages 53-73
    4. Bruce R. Smoller
      Pages 75-109
    5. Bruce R. Smoller
      Pages 111-125
    6. Bruce R. Smoller
      Pages 145-153
    7. Bruce R. Smoller
      Pages 155-160
  4. Vignettes

    1. Front Matter
      Pages 161-161
    2. Bruce R. Smoller
      Pages 163-192
  5. Back Matter
    Pages 193-198

About this book


Although immunostaining has become an integral and essential part of the diagnostic pathology of the skin, its uses, abuses, and limitations are not fully appreciated. In Practical Immunopathology of the Skin, Bruce R. Smoller, md, concisely reviews for practitioners and students alike the science of immunopathology, its many basic laboratory tools, and their multiple diagnostic uses in actual clinical case studies. The author presents in an easily digestible form a dictionary of antibody probes, summarizing for each antibody the targeted antigen and its cellular function, its diagnostic utility, and, when available, its sensitivities and specificities for identifying various neoplasms. The more specific technical aspects and the potentially confounding features of each antibody are also included, along with the author's personal experiences with them in the laboratory. Real clinical cases from the author's practice demonstrate the benefits of immunopathology. Each case offers a clinical history, photomicrographs from the first stained microscopic sections, a differential diagnosis based on the available information, a strategy in tabular form for solving the diagnostic dilemma, and a critical review of the results of that strategy.
User-friendly and highly instructive, Practical Immunopathology of the Skin provides today's dermatologist in training or active practice a working repertoire of useful antibodies and techniques for confidently solving both experimental and clinical diagnostic challenges.


Antigen diseases infectious disease pathology skin

Authors and affiliations

  • Bruce R. Smoller
    • 1
  1. 1.Department of Pathology and DermatologyUniversity of Arkansas for Medical SciencesLittle RockUSA

Bibliographic information