Principles of Molecular Oncology

  • Miguel H. Bronchud
  • Mary Ann Foote
  • William P. Peters
  • Murray O. Robinson

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Molecular Markers

    1. Front Matter
      Pages 1-1
    2. Miguel H. Bronchud, William P. Peters
      Pages 3-27
    3. Daniel F. Hayes
      Pages 29-44
    4. S. Birindelli, A. Aiello, C. Lavarino, G. Sozzi, Silvana Pilotti, Marco A. Pierotti
      Pages 45-93
    5. Thomas Lindahl, Torbjön Norberg, Gunnar Åström, Sigrid Sjögren, C. Jonas Bergh
      Pages 95-110
    6. Alan Horwich, Gill Ross
      Pages 111-124
  3. Diseased Regulatory Pathways

    1. Front Matter
      Pages 125-125
    2. Daniel Kalderon
      Pages 127-167
    3. Hong Liu, V. Craig Jordan
      Pages 169-196
    4. Leonardo Brizuela, Jeno Gyuris, Muzammil Mansuri
      Pages 197-236
    5. Caroline Archer, Peter Trott, Mitchell Dowsett
      Pages 237-255
    6. Murray O. Robinson
      Pages 257-270
    7. Jaume Piulats, Francesc Mitjans
      Pages 271-295
    8. Maria Rosa Bani, Raffaella Giavazzi
      Pages 297-321
    9. Christos Tolis, Carlos G. Ferreira, Herbert M. Pinedo, Giuseppe Giaccone
      Pages 323-356
  4. Future Directions

    1. Front Matter
      Pages 357-357
    2. Angelo A. Cardoso
      Pages 359-394
    3. Matthew Moyle, Michael Palazzolo
      Pages 395-410
    4. Karol Sikora
      Pages 411-420
    5. Paul Workman
      Pages 421-437
  5. Back Matter
    Pages 439-452

About this book


"...provides a bold new look at the evolution of our knowledge of cancer...will prove both informative and intellectually satisfying." -- E. Donnall Thomas, MD

"...[an] excellent book... -- Professor Sir David J. Weatherall, FRS, Regius Professor of Medicine, University of Oxford

In Principles of Molecular Oncology, award winning basic scientists and clinical researchers summarize the wealth of new molecular knowledge that sees cancer as a "disease process" involving key regulatory pathways. Emphasizing prevention, early diagnosis, prognosis, and treatment, these authoritative experts from around the world
illuminate the variety of molecular markers to be found, interpret what is known about diseased regulatory pathways, and examine those future research directions likely to realize the promise of molecular therapy. From their presentations, readers will gain an understanding of why current therapies work or fail, and of the new processes now available to identify specific molecular targets for optimal therapeutic efficacy. Rational therapies designed to target metastatic progression are also critically reviewed.

Comprehensive and pathbreaking, Principles of Molecular Oncology offers both basic and clinical oncologists not only a bold synthesis of the rapid and complex advances in molecular biology that are transforming our knowledge of cancer, but also a highly practical guide to today's best strategies for its diagnosis and treatment.


DNA DNA repair angiogenesis apoptosis biology clinical trial genetics immunity leukemia metastasis molecular biology pharmacology prevention surgery tissue

Editors and affiliations

  • Miguel H. Bronchud
    • 1
  • Mary Ann Foote
    • 2
  • William P. Peters
    • 3
  • Murray O. Robinson
    • 2
  1. 1.Hospital General of GranollersBarcelonaSpain
  2. 2.Amgen Inc.Thousand OaksUSA
  3. 3.Barbara Ann Karmonos Cancer Institute, The Detroit Medical CenterWayne State UniversityDetroitUSA

Bibliographic information