Basic Research and Clinical Applications

  • Jeffrey L. Platt

Table of contents

  1. Front Matter
    Pages i-x
  2. Matilde Bustos, Jeffrey L. Platt
    Pages 45-55
  3. Uri Galili
    Pages 57-71
  4. William Parker, Paul B. Yu, Yuko C. Nakamura
    Pages 73-85
  5. William Parker, Ryan C. Fields, Yuko C. Nakamura
    Pages 87-101
  6. Mauro S. Sandrin, Ian F. C. McKenzie
    Pages 119-137
  7. Agustin P. Dalmasso
    Pages 139-171
  8. Nicola Rogers, Robert Lechler
    Pages 173-197
  9. Antonello Pileggi, R. Damaris Molano, Thierry Berney, Luca Inverardi
    Pages 199-214
  10. Albert S. B. Edge
    Pages 247-263
  11. Back Matter
    Pages 265-270

About this book


Xenotransplantation might well provide a revolutionary way of augmenting the function of diseased tissues or replacing organs. This possibility has been advanced by newly acquired understanding of the biological and immunological obstacles to conducting transplantation between species. In Xenotransplantation: Basic Research and Clinical Applications, internationally recognized scientists, clinicians, and technologists review and explain the fundamental molecular and cellular biology that has been applied to the emerging field of transplant immunology and xenotransplantation and what impact these advances might optimally have on medicine and science. The authoritative experts writing here-many of whom made the basic discoveries underlying the recent advances-examine the biological and immunological hurdles to xenotransplantation, illuminating how the immune system interacts with the xenograft, and laying a practical foundation for the use of genetic engineering and animal transplants in the treatment of human disease.
Comprehensive and authoritative, Xenotransplantation: Basic Research and Clinical Applications provides basic and clinical investigators, as well as transplant surgeons, with today's most thorough and up-to-date compendium of vital information on all the scientific and technological aspects of xenotransplantation.


antibody antigen immune system immunity immunology transplantation

Editors and affiliations

  • Jeffrey L. Platt
    • 1
  1. 1.Transplantation Biology and the Departments of Surgery, Immunology, and PediatricsMayo ClinicRochesterUSA

Bibliographic information