Introduction to Proteomics

Tools for the New Biology

  • Daniel C. Liebler

Table of contents

  1. Front Matter
    Pages i-ix
  2. Proteomics and the Proteome

    1. Front Matter
      Pages 1-1
    2. Daniel C. Liebler
      Pages 3-13
    3. Daniel C. Liebler
      Pages 15-24
  3. Tools of Proteomics

    1. Front Matter
      Pages 25-25
    2. Daniel C. Liebler
      Pages 27-29
    3. Daniel C. Liebler
      Pages 31-48
    4. Daniel C. Liebler
      Pages 49-54
  4. Applications of Proteomics

    1. Front Matter
      Pages 123-123
    2. Daniel C. Liebler
      Pages 125-135
    3. Daniel C. Liebler
      Pages 137-149
    4. Daniel C. Liebler
      Pages 167-184
    5. Daniel C. Liebler
      Pages 185-193
  5. Back Matter
    Pages 195-198

About this book

Introduction

Advances in genome sequencing, analytical instrumentation, and computing power have excitingly transformed the practice of biology by now making it possible to understand complex biological systems as collections of proteins-proteomes. In Introduction to Proteomics: Tools for the New Biology, Daniel C. Liebler masterfully introduces the science of proteomics by spelling out the basics of how one analyzes proteins and proteomes, and just how these approaches are then employed to investigate their roles in living systems. He explains the key concepts of proteomics, how the analytical instrumentation works, what data mining and other software tools do, and how these tools can be integrated to study proteomes. Also discussed are how protein and peptide separation techniques are applied in proteomics, how mass spectrometry is used to identify proteins, and how data analysis software enables protein identification and the mapping of modifications. In addition, there are proteomic approaches for analyzing differential protein expression, characterizing proteomic diversity, and dissecting protein-protein interactions and networks.
Comprehensive, concise, and easy-to-read, Introduction to Proteomics: Tools for the New Biology provides researchers new to proteomics with all the essential concepts and background needed to use the powerful new proteomic techniques in their research, to make intelligent requests to proteomics service facilities, and to better understand and utilize the rapidly growing proteomics literature.

Keywords

Proteomics protein protein complexes research

Authors and affiliations

  • Daniel C. Liebler
    • 1
  1. 1.College of PharmacyThe University of ArizonaTucsonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-59259-130-5
  • Copyright Information Humana Press 2002
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Book Archive
  • Print ISBN 978-0-89603-992-6
  • Online ISBN 978-1-59259-130-5
  • About this book