Brain Tumor Immunotherapy

  • Linda M. Liau
  • Donald P. Becker
  • Timothy F. Cloughesy
  • Darell D. Bigner

Table of contents

  1. Front Matter
    Pages i-xi
  2. Introduction to the Disease

    1. Front Matter
      Pages 1-1
    2. Paul S. Mischel, Harry V. Vinters
      Pages 3-45
    3. Susan Preston-Martin, Faith Davis, Roberta McKean-Cowdin
      Pages 47-71
    4. John M. Duff, Pierre-Yves Dietrich, Nicolas de Tribolet
      Pages 73-87
  3. Introduction to Immunotherapy of Brain Tumors

    1. Front Matter
      Pages 89-89
    2. Victor C. K. Tse, Frances K. Conley
      Pages 91-99
    3. Amy B. Heimberger, Darell D. Bigner, John H. Sampson
      Pages 101-130
  4. Adoptive Cellular Immunotherapy of Brain Tumors

  5. Antibody-Mediated Immunotherapy of Brain Tumors

    1. Front Matter
      Pages 191-191
    2. Carol J. Wikstrand, Michael R. Zalutsky, Darell D. Bigner
      Pages 205-229
    3. Walter A. Hall
      Pages 231-247
  6. Tumor Vaccines and Other Strategies

    1. Front Matter
      Pages 271-271
    2. Roberta P. Glick, Terry Lichtor, Edward P. Cohen
      Pages 273-288
    3. Habib Fakhrai, Svetlana Gramatikova, Rohangiz Safaei
      Pages 289-305
    4. Stéphane Vandenabeele, Linda M. Liau, David Ashley
      Pages 307-325
  7. Back Matter
    Pages 363-373

About this book


It is now clear from basic research and clinical trials that immunotherapy for brain tumors is feasible, can evoke relevant biologic responses, and can yield important insights into human biology. In Brain Tumor Immunotherapy, an authoritative panel of researchers and clinicians critically reviews the entire field to provide a comprehensive guide to modern brain tumor immunotherapy and thereby enhance future research in this area. The contributors detail many of the key laboratory experiments and clinical protocols that are currently being investigated, integrate the available information from previous and ongoing research, and help define the current status of the field. Topics range from adoptive cellular and antibody-mediated immunotherapy of brain tumors to tumor vaccines and related strategies, and include many vanguard experimental strategies and immunological techniques for studying tumor immunotherapy. Introductory material brings the reader up-to-date on the biological principles of brain tumor immunotherapy, along with the neuropathology, molecular pathogenesis, epidemiology, and the relevant current therapies.
Cutting-edge and comprehensive, Brain Tumor Immunotherapy brings together all the important recent advances in our understanding of central nervous system tumor immunology and illustrates in powerful detail the many new applications now harnessing the immune response for brain tumor therapeutics.


apoptosis brain brain tumor brain tumors cell central nervous system gene therapy immunotherapy lymphocytes nervous system neuropathology pathogenesis pathology tumor

Editors and affiliations

  • Linda M. Liau
    • 1
  • Donald P. Becker
    • 1
  • Timothy F. Cloughesy
    • 1
  • Darell D. Bigner
    • 2
  1. 1.School of MedicineUniversity of California at Los AngelesUSA
  2. 2.Department of Pathology and Duke Comprehensive Cancer CenterDuke University Medical CenterDurhamUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2001
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-61737-110-3
  • Online ISBN 978-1-59259-035-3
  • Buy this book on publisher's site