Early Diagnosis of Alzheimer’s Disease

  • Leonard F. M. Scinto
  • Kirk R. Daffner

Part of the Current Clinical Neurology book series (CCNEU)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Kirk R. Daffner, Leonard F. M. Scinto
    Pages 1-27
  3. Dennis J. Selkoe
    Pages 83-104
  4. Deborah Blacker, Rudolph E. Tanzi
    Pages 105-125
  5. Clifford R. Jack Jr., Ronald C. Petersen
    Pages 127-148
  6. Reisa A. Sperling, Thomas A. Sandson, Keith A. Johnson
    Pages 149-168
  7. Dorene M. Rentz, Sandra Weintraub
    Pages 169-189
  8. Maire E. Percy, David F. Andrews, Huntington Potter
    Pages 191-268
  9. Kenneth S. Kosik, Stephen G. Post, Kimberly A. Quaid
    Pages 317-327
  10. Back Matter
    Pages 329-359

About this book


Strategies for the early diagnosis of Alzheimer's disease are among the most important and most discussed topics in dementia care today. In Early Diagnosis of Alzheimer's Disease, Drs. Leonard Scinto and Kirk Daffner provide a comprehensive survey of today's new diagnostic approaches to Alzheimer's disease. Leaders in the field critically survey the most promising clinical research on early diagnostic markers for Alzheimer's disease, including the elucidation of changes in the brain revealed by structural and functional neuroimaging, as well as the characteristic patterns of cognitive decline that are documented by sensitive neuropsychological tests, various genetic markers, and biological assays. In addition, there are reviews of current clinical practice in the diagnosis of Alzheimer's disease, the major theories about its pathophysiology, and the therapeutic and ethical implications of early diagnosis. Early Diagnosis of Alzheimer's Disease illuminates the complex issues surrounding the search for early markers of this highly prevalent disease. Addressed to clinicians caring for an aging population, researchers developing new therapeutics, and policymakers concerned about the impact of early diagnosis on the delivery of health care, this timely, state-of-the-art volume constitutes a new standard reference guide for all those working with Alzheimer's patients today.


Alzheimer PET SPECT alzheimer's disease brain magnetic resonance imaging (MRI) neuropathology pathophysiology physiology positron emission tomography (PET)

Editors and affiliations

  • Leonard F. M. Scinto
    • 1
  • Kirk R. Daffner
    • 1
  1. 1.Department of Neurology, Brigham and Women’s HospitalHarvard Medical SchoolBostonUSA

Bibliographic information