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Omics Approaches to Understanding Muscle Biology

  • Jatin George Burniston
  • Yi-Wen Chen
Book

Part of the Methods in Physiology book series (METHPHYS)

Table of contents

  1. Front Matter
    Pages i-vii
  2. Stefano Schiaffino, Carlo Reggiani, Marta Murgia
    Pages 1-6
  3. Genomic and Epi-genomic

    1. Front Matter
      Pages 7-7
    2. Luca Bello, Elena Pegoraro, Eric P. Hoffman
      Pages 9-30
    3. Surajit Bhattacharya, Heather Gordish-Dressman
      Pages 45-75
  4. Transcriptomic

    1. Front Matter
      Pages 77-77
    2. Poching Liu, Surajit Bhattacharya, Yi-Wen Chen
      Pages 79-107
    3. Alyson A. Fiorillo, Christopher R. Heier
      Pages 109-133
  5. Proteomic

    1. Front Matter
      Pages 135-135
    2. Paul R. Langlais, Lawrence J. Mandarino
      Pages 137-154
    3. Emily Canessa, Mansi V. Goswami, Alison M. Samsel, Michael Ogundele, Shefa M. Tawalbeh, Tchilabalo D. Alayi et al.
      Pages 155-169
  6. Metabolomic

    1. Front Matter
      Pages 191-191
    2. Kenneth Allen Dyar, Anna Artati, Alexander Cecil, Jerzy Adamski
      Pages 193-217

About this book

Introduction

This book is a collection of principles and current practices in omics research, applied to skeletal muscle physiology and disorders. The various sections are categorized according to the level of biological organization, namely, genomics (DNA), transcriptomics (RNA), proteomics (protein), and metabolomics (metabolite). With skeletal muscle as the unifying theme, and featuring contributions from leading experts in this traditional field of research, it highlights the importance of skeletal muscle tissue in human development, health and successful ageing. It also discusses other fascinating topics like developmental biology, muscular dystrophies, exercise, insulin resistance and atrophy due to disuse, ageing or other muscle diseases, conveying the vast opportunities for generating new hypotheses as well as testing existing hypotheses by combining high-throughput techniques with proper experiment designs, bioinformatics and statistical analyses.

Presenting the latest research techniques, this book is a valuable resource for the physiology community, particularly researchers and grad students who want to explore the new opportunities for omics technologies in basic physiology research.

Keywords

Skeletal muscle Skeletal muscle physiology skeletal muscle development OMICS technologies muscular dystrophy high-throughput analytical techniques RNA profiling muscle atrophy and dysfunction

Editors and affiliations

  • Jatin George Burniston
    • 1
  • Yi-Wen Chen
    • 2
  1. 1.Research Institute for Sport and Exercise SciencesLiverpool John Moores UniversityLiverpoolUK
  2. 2.Children’s National Health SystemGeorge Washington UniversityWashington, DCUSA

Bibliographic information