Psychiatric Disorders

Methods and Protocols

  • Firas H. Kobeissy

Part of the Methods in Molecular Biology book series (MIMB, volume 2011)

Table of contents

  1. Front Matter
    Pages i-xxiii
  2. Overview of the Animal Research in Psychiatric Illness

    1. Front Matter
      Pages 1-1
    2. Arie Kaffman, Jordon D. White, Lan Wei, Frances K. Johnson, John H. Krystal
      Pages 3-22
    3. A. Benjamin Srivastava, Firas H. Kobeissy, Mark S. Gold
      Pages 23-37
  3. Overview of Animal Models of Psychiatric Illness

    1. Front Matter
      Pages 39-39
    2. Nadja Freund, Georg Juckel
      Pages 61-77
    3. Caitlin A. Orsini, Shelby L. Blaes, Barry Setlow, Nicholas W. Simon
      Pages 79-92
  4. Methods of Animal Models of Psychiatric Illness

    1. Front Matter
      Pages 93-93
    2. Alicia Izquierdo, Claudia Aguirre, Evan E. Hart, Alexandra Stolyarova
      Pages 105-119
    3. Abdellatif Abbaoui, Lahcen Tamegart, Halima Gamrani
      Pages 133-142
    4. Hajar Benmhammed, Samer El Hayek, Inssaf Berkik, Hicham Elmostafi, Rim Bousalham, Abdelhalem Mesfioui et al.
      Pages 143-161
  5. Overview of Animal Models of Substance Abuse

    1. Front Matter
      Pages 163-163
    2. Chidera C. Chukwueke, Bernard Le Foll
      Pages 195-219
    3. Hiba Hasan, Samar Abdelhady, Muhammad Haidar, Christina Fakih, Samer El Hayek, Stefania Mondello et al.
      Pages 221-250
  6. Methods of Animal Models of Substance Abuse

    1. Front Matter
      Pages 251-251
    2. Brandon Levin, Isaac Wilks, Sijie Tan, Azin Behnood-Rod, Adriaan Bruijnzeel
      Pages 253-265
    3. Patricia Mesa-Gresa, Aránzazu Duque, Santiago Monleón, Concepción Vinader-Caerols, Rosa Redolat
      Pages 267-280
    4. Santiago Monleón, Aránzazu Duque, Patricia Mesa-Gresa, Rosa Redolat, Concepción Vinader-Caerols
      Pages 281-293
  7. Methods of Animal Models of Eating Disorders

    1. Front Matter
      Pages 295-295
    2. Maria Scherma, Roberto Collu, Valentina Satta, Elisa Giunti, Paola Fadda
      Pages 297-314
  8. Review of Animal Models of Aging, Neurodegenerative Diseases and Traumatic Brain Injury

    1. Front Matter
      Pages 329-329
    2. Lei Zhang, Xian-Zhang Hu, He Li, Xiaoxia Li, Tianzheng Yu, Jacob Dohl et al.
      Pages 331-344
    3. Yasser Medlej, Houssein Salah, Lara Wadi, Sarah Saad, Rita Asdikian, Nabil Karnib et al.
      Pages 345-367
  9. Methods of Animal Models of Aging, Neurodegenerative Diseases and Traumatic Brain Injury

    1. Front Matter
      Pages 369-369
    2. Hale Z. Toklu, Zhiui Yang, Mehmet Ersahin, Kevin K. W. Wang
      Pages 371-381
    3. Houssein Salah, Yasser Medlej, Nabil Karnib, Nora Darwish, Rita Asdikian, Sarah Wehbe et al.
      Pages 413-427
    4. Yasser Medlej, Houssein Salah, Lara Wadi, Zahraa Atoui, Yasser Fadlallah, Rita Asdikian et al.
      Pages 429-439
    5. Sara El-Desouky, Yasmeen M. Taalab, Mohamed El-Gamal, Wael Mohamed, Mohamed Salama
      Pages 451-464
  10. Inflammatory and Metabolic Profiles Relevant to Neuropsychiatric Disorders

    1. Front Matter
      Pages 465-465
    2. J. P. Brás, S. Pinto, M. I. Almeida, J. Prata, O. von Doellinger, R. Coelho et al.
      Pages 467-492
    3. J. Prata, A. S. Machado, O. von Doellinger, M. I. Almeida, M. A. Barbosa, R. Coelho et al.
      Pages 493-510
    4. Navneet Dhaliwal, Jatinder Dhaliwal, Dhirendra Pratap Singh, Kanthi Kiran Kondepudi, Mahendra Bishnoi, Kanwaljit Chopra
      Pages 531-544
  11. Overview and Methods of Genetic Animal Models of Neuropsychiatric Disorders

    1. Front Matter
      Pages 545-545
    2. Yanjie Qi, Yi Zheng, Zhanjiang Li, Zhisheng Liu, Lan Xiong
      Pages 547-571
    3. Eunice W. M. Chin, Eyleen L. K. Goh
      Pages 573-591
  12. Role of Genetics, Molecular Techniques, and Epigenetics in Neuropsychiatric Disorders

About this book


This second edition volume expands on the previous edition with updates to chapters and new chapters discussing the latest research in neuropsychiatric diseases. The chapters in this book are organized into eleven sections and cover the diversity and utility of animal models of psychiatric disorders, their development, modeling, and pathophysiological and molecular profiles. Part One looks at experimental modeling of neuropsychiatric studies and the usefulness and need of animal models. Parts Two and Three focus on experimental models of neuropsychiatric illnesses, including self-injurious behavior, bipolar disorder, anxiety, and learning and decision-making testing. Parts Four and Five discuss animal models of substance abuse. Part Six describes protocols to examine animal models related to maladaptive eating habits and behaviors. Parts Seven and Eight cover neurodegenerative diseases stemming from natural causes (aging), abnormal genetic backgrounds, or those brought on by trauma. Part Nine talks about inflammatory and metabolic alteration profiles relevant to autism spectrum disorders and depression. Parts Ten and Eleven conclude the book with a discussion on genetics, epigenetics, and system biology in the field of psychiatric disorders. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and thorough, Psychiatric Disorders: Methods and Protocols, Second Edition is a useful resource for graduates, postdoctoral workers, and established scientists working in the fields of behavioral and molecular neuropsychiatric research.   


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Editors and affiliations

  • Firas H. Kobeissy
    • 1
  1. 1.Department of Biochemistry and Molecular Genetics, Faculty of MedicineAmerican University of BeirutBeirutLebanon

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC, part of Springer Nature 2019
  • Publisher Name Humana, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-9553-0
  • Online ISBN 978-1-4939-9554-7
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site