FOXO Transcription Factors

Methods and Protocols

  • Wolfgang Link

Part of the Methods in Molecular Biology book series (MIMB, volume 1890)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Wolfgang Link
    Pages 1-9
  3. Biochemical and Molecular Methods

    1. Front Matter
      Pages 11-11
    2. Doug Hanniford, Eva Hernando
      Pages 13-28
    3. Alba Orea-Soufi, David Dávila, María Salazar-Roa, María de Mar Lorente, Guillermo Velasco
      Pages 51-59
    4. María Monsalve, Ignacio Prieto, Andreza Fabro de Bem, Yolanda Olmos
      Pages 61-76
    5. Shang Yao, Zimam Mahmud, Nikoleta Sachini, Sathid Aimjongjun, Paula Saavedra-García, Eric W-F Lam
      Pages 77-90
    6. Antonia Ávila-Flores, Javier Arranz-Nicolás, Isabel Mérida
      Pages 91-102
    7. Vanessa Henriques, Susana Machado, Wolfgang Link, Bibiana I. Ferreira
      Pages 103-113
    8. Priyankar Sanphui, Akash Saha, Subhas Chandra Biswas
      Pages 131-140
  4. Imaging Approaches

    1. Front Matter
      Pages 141-141
    2. Francisco Castillo, Thomas A. Mackenzie, Bastien Cautain
      Pages 143-149
    3. Marta Barradas, Wolfgang Link, Diego Megias, Pablo J. Fernandez-Marcos
      Pages 151-161
    4. Susana Machado, Catarina Raposo, Bibiana I. Ferreira, Wolfgang Link
      Pages 163-170
    5. Anna C. Blice-Baum, Georg Vogler, Meera C. Viswanathan, Bosco Trinh, Worawan B. Limpitikul, Anthony Cammarato
      Pages 171-190
  5. Omics and Bioinformatic Approaches

    1. Front Matter
      Pages 191-191
    2. Dong-Ju Shin, Pujan Joshi, Dong-Guk Shin, Li Wang
      Pages 193-203
    3. Bradford E. Peercy, Martin F. Schneider
      Pages 205-217
    4. Raymond Liang, Vijay Menon, Saghi Ghaffari
      Pages 219-227
  6. Animal Models

    1. Front Matter
      Pages 229-229
  7. Human Genetic and Clinical Studies

    1. Front Matter
      Pages 249-249
    2. Timothy A. Donlon, Philip M. C. Davy, Bradley J. Willcox
      Pages 251-257
    3. Tejas Shah, Kalpana Joshi
      Pages 259-266
  8. Back Matter
    Pages 267-270

About this book


This volume provides an overview of experimental procedures and state-of art methods to investigate FOXOs. Chapters guide readers through biochemical and molecular methods, imaging approaches to monitor the subcellular localization of FOXO factors, omics and bioinformatics approaches, different animal models used in FOXO research, and human studies to investigate the role of FOXO factors in human disease and longevity. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.


Authoritative and cutting-edge FOXO Transcription Factors: Methods and Protocols aims to ensure successful results in the further study of this vital field.


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Editors and affiliations

  • Wolfgang Link
    • 1
  1. 1.Instituto de Investigaciones Biomédicas “Alberto Sols” (CSIC-UAM)MadridSpain

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC, part of Springer Nature 2019
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-8899-0
  • Online ISBN 978-1-4939-8900-3
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site