Experimental Models of Cardiovascular Diseases

Methods and Protocols

  • Kiyotake Ishikawa

Part of the Methods in Molecular Biology book series (MIMB, volume 1816)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Overview

    1. Front Matter
      Pages 1-1
    2. Jae Gyun Oh, Kiyotake Ishikawa
      Pages 3-14
  3. In Silico Models

    1. Front Matter
      Pages 15-15
    2. Joshua Mayourian, Eric A. Sobie, Kevin D. Costa
      Pages 17-35
  4. In Vitro Models

    1. Front Matter
      Pages 37-37
    2. Jelena Plačkić, Jens Kockskämper
      Pages 39-54
    3. Adam T. Lynch, Silvia Mazzotta, Stefan Hoppler
      Pages 55-66
    4. Silvia Mazzotta, Adam T. Lynch, Stefan Hoppler
      Pages 67-78
    5. Takeshi Hatani, Kenji Miki, Yoshinori Yoshida
      Pages 79-92
    6. Przemek A. Gorski, Changwon Kho, Jae Gyun Oh
      Pages 93-104
  5. Ex Vivo Models

    1. Front Matter
      Pages 105-105
    2. Irene C. Turnbull, Joshua Mayourian, Jack F. Murphy, Francesca Stillitano, Delaine K. Ceholski, Kevin D. Costa
      Pages 145-159
    3. M. Urooj Zafar, Carlos G. Santos-Gallego, Lina Badimon, Juan J. Badimon
      Pages 161-171
  6. Small Animal Models

    1. Front Matter
      Pages 173-173
    2. Jiqiu Chen, Delaine K. Ceholski, Irene C. Turnbull, Lifan Liang, Roger J. Hajjar
      Pages 175-182
    3. Jimeen Yoo, Vadim Chepurko, Roger J. Hajjar, Dongtak Jeong
      Pages 183-193
    4. Sunny C. Chang, Shuxun Ren, Christoph D. Rau, Jessica J. Wang
      Pages 207-220
    5. Takehiro Nakahara, Takashi Tanimoto, Artiom D. Petrov, Kiyotake Ishikawa, H. William Strauss, Jagat Narula
      Pages 221-232
    6. Carlos Bueno-Beti, Yassine Sassi, Roger J. Hajjar, Lahouaria Hadri
      Pages 233-241
    7. Carlos Bueno-Beti, Lahouaria Hadri, Roger J. Hajjar, Yassine Sassi
      Pages 243-252
    8. Aya Nomura-Kitabayashi, Jason C. Kovacic
      Pages 253-268
    9. Toshihiko Isaji, Alan Dardik
      Pages 269-277
  7. Large Animal Models

    1. Front Matter
      Pages 279-279
    2. Olympia Bikou, Shin Watanabe, Roger J. Hajjar, Kiyotake Ishikawa
      Pages 281-294
    3. Dae-Hee Kim, Brittan Morris, J. Luis Guerrero, Suzanne M. Sullivan, Judy Hung, Robert A. Levine
      Pages 295-308
    4. Jeffery C. Powers, Fabio Recchia
      Pages 309-325
    5. Shin Watanabe, Olympia Bikou, Roger J. Hajjar, Kiyotake Ishikawa
      Pages 327-335
    6. Olympia Bikou, Satoshi Miyashita, Kiyotake Ishikawa
      Pages 337-342
    7. Ole K. Møller-Helgestad, Hanne B. Ravn, Jacob E. Møller
      Pages 343-352
    8. Jaume Aguero, Nadjib Hammoudi, Olympia Bikou, Kenneth M. Fish, Iratxe Zarragoikoetxea, Roger J. Hajjar et al.
      Pages 353-366
    9. Olympia Bikou, Kiyotake Ishikawa, Kenneth M. Fish, Iratxe Zarragoikoetxea, Roger J. Hajjar, Jaume Aguero
      Pages 367-383
    10. Max L. Senders, Mark E. Lobatto, Raphael Soler, Olivier Lairez, Carlos Pérez-Medina, Claudia Calcagno et al.
      Pages 385-400
  8. Back Matter
    Pages 401-404

About this book


T​his book provides methodological information on establishing reliable and reproducible experimental models of cardiovascular diseases. Chapters detail practical protocols from expert laboratories focusing on cardiovascular research, leading to novel discoveries in cardiac biology, and the development of effective therapeutic approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 Authoritative and cutting-edge, Experimental Models of Cardiovascular Disease: Methods and Protocols aims to ensure successful results in the further study of this vital field.


in silico models cardiac physiology cardiomyocytes Optical Mapping arrhythmia

Editors and affiliations

  • Kiyotake Ishikawa
    • 1
  1. 1.Icahn School of Medicine at Mount SinaiNew YorkUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC, part of Springer Nature 2018
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-8596-8
  • Online ISBN 978-1-4939-8597-5
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site