Mechanisms Underlying Host-Microbiome Interactions in Pathophysiology of Human Diseases

  • Jun Sun
  • Pradeep K. Dudeja

Part of the Physiology in Health and Disease book series (PIHD)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Ozge Nur Aktas, Benjamin Turturice, David L. Perkins, Patricia W. Finn
    Pages 35-53
  3. Anoop Kumar, Pradhan Bhat, Alip Borthakur, Waddah A. Alrefai, Pradeep K. Dudeja
    Pages 89-111
  4. Shreya Raja, Vivek Batra, Shanthi Srinivasan
    Pages 113-127
  5. Beng San Yeoh, Matam Vijay-Kumar
    Pages 129-165
  6. Melissa C. Kordahi, R. William DePaolo
    Pages 167-193
  7. Adrian A. Vasquez, Jeffrey L. Ram, Milad S. Qazazi, Jun Sun, Ikuko Kato
    Pages 195-246
  8. Changbin Chen, Xinhua Huang
    Pages 247-278
  9. Roxana Chis, Prameet M. Sheth, Elaine O. Petrof
    Pages 279-302
  10. Back Matter
    Pages 373-381

About this book


Only recently have we begun to appreciate the role of microbiome in health and disease. Environmental factors and change of life style including diet significantly shape human microbiome that in turn appears to modify gut barrier function affecting nutrient & electrolyte absorption and inflammation. Approaches that can reverse the gut dysbiosis represent as reasonable and novel strategies for restoring the balance between host and microbes.

In the book, we offer summary and discussion on the advances in understanding of pathophysiological mechanisms of microbial host interactions in human diseases. We will not only discuss intestinal bacterial community, but also viruses, fungi and oral microbiome. Microbiome studies will facilitate diagnosis, functional studies, drug development and personalized medicine. Thus, this book will further highlight the microbiome in the context of health and disease, focusing on mechanistic concepts that underlie the complex relationships between host and microbes.


Microbiome Organoids Obesity Metabolism Animal Models Inflammation Infection Cancer

Editors and affiliations

  • Jun Sun
    • 1
  • Pradeep K. Dudeja
    • 2
  1. 1.Division of Gastroenterology and Hepatology, Department of MedicineUniversity of Illinois at ChicagoChicagoUSA
  2. 2.Division of Gastroenterology and Hepatology, Department of MedicineUniversity of Illinois at ChicagoChicagoUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC, part of Springer Nature 2018
  • Publisher Name Springer, Boston, MA
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4939-7533-4
  • Online ISBN 978-1-4939-7534-1
  • Buy this book on publisher's site