Overview
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1709)
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Table of contents (29 protocols)
Keywords
About this book
This volume is a compilation of laboratory protocols and methodology required for the study of molecular chaperones and the cellular stress response. Chapters detail stress response in Hsf1, Hsf2 and Hsf4 knockout mice, mapping HSP interaction networks, the LUminescence-based Mammalian IntERactome (LUMIER), Hsp70 biology, protein folding activity of Hsp90, cytotoxicity of HSP inhibitors, computational approaches for modeling allosteric Hsp90 interactions, HSPs in immunity and vaccine development , and biologies of Hsp70 and Hsp90. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Chaperones: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Editors and Affiliations
Bibliographic Information
Book Title: Chaperones
Book Subtitle: Methods and Protocols
Editors: Stuart K. Calderwood, Thomas L. Prince
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-7477-1
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2018
Hardcover ISBN: 978-1-4939-7476-4Published: 26 November 2017
Softcover ISBN: 978-1-4939-8498-5Published: 05 September 2018
eBook ISBN: 978-1-4939-7477-1Published: 24 November 2017
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XIX, 445
Number of Illustrations: 33 b/w illustrations, 36 illustrations in colour
Topics: Biochemistry, general