ErbB Receptor Signaling

Methods and Protocols

  • Zhixiang Wang

Part of the Methods in Molecular Biology book series (MIMB, volume 1652)

Table of contents

  1. Front Matter
    Pages i-x
  2. Introduction and Review

    1. Front Matter
      Pages 1-1
    2. Zhixiang Wang
      Pages 3-35
    3. Xiaofu Zhu, Anil Abraham Joy
      Pages 63-77
  3. Classical Methods in the Studies of ErbB Receptor Signaling

  4. Recently Developed Methods in the Studies of ErbB Receptor Signaling

    1. Front Matter
      Pages 165-165
    2. Stefanie Lucarelli, Ralph Christian Delos Santos, Costin N. Antonescu
      Pages 191-225
  5. Methods for Studying EGFR Signaling in Drosophila

  6. Methods Related to the Translational Research of ErbB Receptor Signaling

    1. Front Matter
      Pages 257-257
    2. Jing-Wen Bai, Yong-Qu Zhang, Yao-Chen Li, Guo-Jun Zhang
      Pages 259-274
    3. Sheena H. MacLeod, Kyle G. Potts, Shyambabu Chaurasiya, Mary M. Hitt
      Pages 275-293
  7. Back Matter
    Pages 301-303

About this book


This volume contains protocols specifically designed for studying cell signaling mediated by ErbB receptors, all applicable to the study of a broad range of ErbB receptor-mediated signaling from basic research to clinic applications, from cultured cells to various animal models and primary cancer cells from patients. After some overviews, the book continues by covering common protocols for studying various aspects of ErbB receptor-mediated cell signaling, newly-developed methods in biomedical research that are also widely-used in the study of ErbB receptor signaling, epidermal growth factor receptor (EGFR) signaling in Drosophila, as well as protocols for studying ErbB receptor signaling in various animal model systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

Detailed and easy-to-follow, ErbB Receptor Signaling: Methods and Protocols serves as an ideal guide for researchers who are studying the cell signaling mediated by ErbB receptors and other receptor tyrosine kinases.


Cell signaling Epidermal growth factor receptor Receptor tyrosine kinases EGF RTKs Cancer research Animal model systems

Editors and affiliations

  • Zhixiang Wang
    • 1
  1. 1.Department of Medical GeneticsUniversity of AlbertaEdmontonCanada

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media LLC 2017
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-7218-0
  • Online ISBN 978-1-4939-7219-7
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site