Vaccines for Invasive Fungal Infections

Methods and Protocols

  • Markus Kalkum
  • Margarita Semis

Part of the Methods in Molecular Biology book series (MIMB, volume 1625)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Discovery and Testing of Vaccine Candidates

    1. Front Matter
      Pages 1-1
    2. Estefânia Mara do Nascimento Martins, Antero Silva Ribeiro de Andrade
      Pages 3-21
    3. Marife Martinez, Karl V. Clemons, David A. Stevens
      Pages 23-30
    4. Rupanjali Chaudhuri, Srinivasan Ramachandran
      Pages 31-43
    5. Bernd Roschitzki, Salomé LeibundGut-Landmann
      Pages 65-74
    6. Alice M. Ribeiro, André C. Amaral, Maria Sueli S. Felipe, Anamelia L. Bocca
      Pages 85-96
    7. Luciano Polonelli, Walter Magliani, Stefania Conti
      Pages 97-112
    8. Carlos P. Taborda, Luiz R. Travassos
      Pages 113-128
    9. Ashok K. Chaturvedi, Floyd L. Wormley Jr
      Pages 129-140
  3. Design and Delivery

    1. Front Matter
      Pages 141-141
    2. Zeynep Mirza, Ernesto R. Soto, Fusun Dikengil, Stuart M. Levitz, Gary R. Ostroff
      Pages 143-157
    3. Thiago Aparecido da Silva, Fabrício Freitas Fernandes, Taise Natali Landgraf, Ademílson Panunto-Castelo, Maria Cristina Roque-Barreira
      Pages 159-167
    4. Swaleha Zubair, Asim Azhar, Nazoora Khan, Ejaj Ahmad, Mohd Ajmal, Mohammad Owais
      Pages 169-211
    5. Aline Ferreira Oliveira, Paulo S. R. Coelho
      Pages 213-224
    6. Yicun Wang, Li Wang
      Pages 225-235
  4. Endpoint Assessment

    1. Front Matter
      Pages 247-247
    2. Vidmantas Petraitis, Ruta Petraitiene, William W. Hope, Thomas J. Walsh
      Pages 259-277
  5. Mechanism of Vaccine Protection

    1. Front Matter
      Pages 279-279
    2. Diana Diaz-Arevalo, Markus Kalkum
      Pages 281-293
    3. Nina Khanna, Claudia Stuehler
      Pages 295-312
    4. Keigo Ueno, Makoto Urai, Shogo Takatsuka, Masahiro Abe, Yoshitsugu Miyazaki, Yuki Kinjo
      Pages 327-339
  6. Translation to Clinical Use

  7. Back Matter
    Pages 355-358

About this book


This detailed volume focuses on the development of mycosis vaccines via the most common etiological agents of mycoses, such as Aspergillus and Candida species, followed by Cryptococcus, dimorphic fungi, and members of Mucoraceae family of fungi. The book is sectioned into five parts that describe experimental approaches for vaccine candidate discovery, improved vaccine design and delivery, assessment of critical endpoints, analysis of mechanisms of mycosis vaccine protection, and key methods for clinical translation. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting known pitfalls. 

Practical and authoritative, Vaccines for Invasive Fungal Infections: Methods and Protocols provides a standard reference for vaccine researchers, including those who aspire to strengthen their knowledge or desire to acquire a particular technique.


Immunosuppressive conditions Fungal pathogens Aspergillus and Candida species Mycoses Invasive mycosis vaccines Endpoint assessment Vaccine design and delivery Clinical translation

Editors and affiliations

  • Markus Kalkum
    • 1
  • Margarita Semis
    • 2
  1. 1.Department of Molecular ImmunologyBeckman Research Institute of City of HopeDuarteUSA
  2. 2.Department of Molecular ImmunologyBeckman Research Institute of City of HopeDuarteUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media LLC 2017
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-7103-9
  • Online ISBN 978-1-4939-7104-6
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site