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Multiparticulate Drug Delivery

Formulation, Processing and Manufacturing

  • Ali R.┬áRajabi-Siahboomi

Part of the Advances in Delivery Science and Technology book series (ADST)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Richard Sidwell, Jason Hansell, Manish Rane, Ali R. Rajabi-Siahboomi
    Pages 5-35
  3. Markus Thommes, Peter Kleinebudde
    Pages 37-63
  4. David M. Jones, Ali R. Rajabi-Siahboomi
    Pages 65-93
  5. Marina Levina, Hue Voung, Ali R. Rajabi-Siahboomi
    Pages 95-118
  6. Sandile M. M. Khamanga, Roderick B. Walker
    Pages 119-154
  7. W. Brett Caldwell, Aditya M. Kaushal
    Pages 155-168
  8. Affiong Iyire, Afzal R. Mohammed
    Pages 213-236
  9. Theresia Kuntz, Wolfgang Weisbrod, Subhashis Chakraborty, Brigitte Skalsky
    Pages 237-266
  10. Ali R. Rajabi-Siahboomi, Raxit Y. Mehta, Vaibhav Ambudkar, Viena Dias, Sandip Tiwari
    Pages 267-299
  11. Stefan Dietrich, Dieter Petrak
    Pages 301-332
  12. Back Matter
    Pages 387-396

About this book

Introduction

Authored by leading experts from academia, users and manufacturers, this book provides an authoritative account of the science and technology involved in multiparticulate drug delivery systems which offer superior clinical and technical advantages over many other specialized approaches in drug delivery. The book will cover market trends, potential benefits and formulation challenges for various types of multiparticulate systems. Drug solubility, dose, chemistry and therapeutic indications as well as excipient suitability coupled with manufacturing methods will be fully covered. Key approaches for taste-masking, delayed release and extended release of multiparticulates systems are of significant interest, especially their in-vivo and in-vitro performance. In addition, the principles of scale-up, QbD, and regulatory aspects of common materials used in this technology will be explained, as well as recent advances in materials and equipment enabling robust, flexible and cost-effective manufacture. Case studies illustrating best practices will also make the book a valuable resource to pharmaceutical scientists in industry and academia.

Keywords

Dissolution Drug Delivery Multiparticulate Pellets Scale-up

Editors and affiliations

  • Ali R.┬áRajabi-Siahboomi
    • 1
  1. 1.VP & Chief Scientific Officer, Colorcon Inc.HarleysvilleUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4939-7012-4
  • Copyright Information Controlled Release Society 2017
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4939-7010-0
  • Online ISBN 978-1-4939-7012-4
  • Series Print ISSN 2192-6204
  • Series Online ISSN 2192-6212
  • Buy this book on publisher's site