Volume II: Structure, Function, and Applications

  • Jonathan M. Keith

Part of the Methods in Molecular Biology book series (MIMB, volume 1526)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Structure, Function, Pathways and Networks

    1. Front Matter
      Pages 1-1
    2. Kala Bharath Pilla, Gottfried Otting, Thomas Huber
      Pages 3-21
    3. Tom C. Giles, Richard D. Emes
      Pages 23-40
    4. Martin A. Smith, John S. Mattick
      Pages 65-85
    5. Gökmen Altay, Onur Mendi
      Pages 99-117
    6. Jan M. Czarnecki, Adrian J. Shepherd
      Pages 139-158
  3. Applications

    1. Front Matter
      Pages 159-159
    2. Allan F. McRae
      Pages 161-173
    3. Russell Thomson, Rebekah McWhirter
      Pages 175-190
    4. David L. Duffy
      Pages 191-203
    5. Claudio Lottaz, Wolfram Gronwald, Rainer Spang, Julia C. Engelmann
      Pages 205-229
    6. Jürgen Bajorath
      Pages 247-256
    7. William D. Lees, Adrian J. Shepherd
      Pages 257-270
    8. Luke Mathieson, Alexandre Mendes, John Marsden, Jeffrey Pond, Pablo Moscato
      Pages 299-325
  4. Computational Methods

    1. Front Matter
      Pages 327-327
    2. G. J. McLachlan, R. W. Bean, S. K. Ng
      Pages 345-362
    3. Falk Hüffner, Christian Komusiewicz, Rolf Niedermeier, Sebastian Wernicke
      Pages 363-402
    4. Tobias Czauderna, Falk Schreiber
      Pages 403-415
  5. Back Matter
    Pages 417-426

About this book


This second edition provides updated and expanded chapters covering a broad sampling of useful and current methods in the rapidly developing and expanding field of bioinformatics. Bioinformatics, Volume II: Structure, Function, and Applications, Second Edition is comprised of three sections: Structure, Function, Pathways and Networks; Applications; and Computational Methods. The first section examines methodologies for understanding biological molecules as systems of interacting elements. The Applications section covers numerous applications of bioinformatics, focusing on analysis of genome-wide association data, computational diagnostic, and drug discovery. The final section describes four broadly applicable computational methods that are important to this field. These are: modeling and inference, clustering, parameterized algorithmics, and visualization. As a volume in the highly successful Methods in Molecular Biology series, chapters feature the kind of detail and expert implementation advice to ensure positive results.

Comprehensive and practical, Bioinformatics, Volume II: Structure, Function, and Applications is an essential resource for graduate students, early career researchers, and others who are in the process of integrating new bioinformatics methods into their research.



genotype phenotype systems of interacting elements genome-wide association data computational diagnostics drug discovery modeling and interference clustering

Editors and affiliations

  • Jonathan M. Keith
    • 1
  1. 1.Monash UniversityMelbourneAustralia

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2017
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-6611-0
  • Online ISBN 978-1-4939-6613-4
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site