Small Molecule Microarrays

Methods and Protocols

  • Mahesh Uttamchandani
  • Shao Q. Yao

Part of the Methods in Molecular Biology book series (MIMB, volume 1518)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Mahesh Uttamchandani, Shao Q. Yao
    Pages 1-17
  3. Dameng Guo, Han Wu, Liang Wu, Bo Zheng
    Pages 19-28
  4. Avijit K. Adak, Ting-Wei Lin, Ben-Yuan Li, Chun-Cheng Lin
    Pages 43-53
  5. Caterina Zilio, Laura Sola, Marina Cretich, Anna Bernardi, Marcella Chiari
    Pages 55-65
  6. Ping Wang, Liqian Gao, Haipeng Lei, Su Seong Lee, Shao Q. Yao, Hongyan Sun
    Pages 67-80
  7. Yung-Shin Sun
    Pages 81-108
  8. Si Ying Png, Sherlyn Xiang Bing Seah, Zhiqiang Gao
    Pages 109-129
  9. Brendan Fu-Long Sieow, Mahesh Uttamchandani
    Pages 131-138
  10. Zhenkun Na, Sijun Pan, Mahesh Uttamchandani, Shao Q. Yao
    Pages 139-156
  11. Colleen M. Connelly, Fardokht A. Abulwerdi, John S. Schneekloth Jr.
    Pages 157-175
  12. Michele Tinti, Simona Panni, Gianni Cesareni
    Pages 177-193
  13. Verena Katharina Meyer, Daniela Meloni, Fabio Olivo, Erwin Märtlbauer, Richard Dietrich, Reinhard Niessner et al.
    Pages 195-212
  14. Felix Broecker, Peter H. Seeberger
    Pages 227-240
  15. Biwei Zhu, Bo Jiang, Zhenkun Na, Shao Q. Yao
    Pages 241-255
  16. Back Matter
    Pages 257-260

About this book


Small molecule microarrays (SMM) were introduced in 1999 and within just a short span of time, have established themselves as a vibrant next generation platform for high-throughput screening. Small Molecule Microarrays: Methods and Protocols consolidates a significant collection of examples, which serve to guide researchers toward ways in which SMM technology may be effectively deployed for multiplexed screening, drug discovery and ligand identification. The volume is organized into three sections covering microarray fabrication, imaging modes, and discovery approaches. The chapters cover a range of small molecule library types, ranging from synthetic combinatorial libraries to peptide and carbohydrate libraries, with lessons and techniques that can be widely applied. Written in the highly successful Methods in Molecular Biology series, format, chapters include introductions of their respective topics, lists of the requisite materials and reagents, step-by-step and readily reproducible laboratory protocols as well as vital tips on troubleshooting and advice on avoiding known pitfalls.


Authoritative and cutting-edge, Small Molecule Microarrays: Methods and Protocols provides meticulous insights into the successful applications of SMM, by experts in the field. Building on this collection of knowledge, the volume seeks to inspire a future generation of microarray practitioners to propel this significant technology to even greater heights



Microarray fabrication Imaging modes small molecules label-free approaches imaging microarrays bona fide ligands peptide microarrays

Editors and affiliations

  • Mahesh Uttamchandani
    • 1
  • Shao Q. Yao
    • 2
  1. 1.DSO National LaboratoriesDefence Medical and Environmental ResearSingaporeSingapore
  2. 2.Department of Chemistry Faculty of ScienceNational University of SingaporeSingaporeSingapore

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2017
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-6582-3
  • Online ISBN 978-1-4939-6584-7
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site