Parental Obesity: Intergenerational Programming and Consequences

  • Lucy R. Green
  • Robert L. Hester

Part of the Physiology in Health and Disease book series (PIHD)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Mark Hanson
    Pages 1-9
  3. J. J. Eckert, M. A. Velazquez, T. P. Fleming
    Pages 81-103
  4. Tod Fullston, Helana S. Shehadeh, John E. Schjenken, Nicole O. McPherson, Sarah A. Robertson, Deirdre Zander-Fox et al.
    Pages 105-131
  5. Laura Dearden, Susan E. Ozanne
    Pages 163-186
  6. Aya Sasaki, Suzanne Erb, Patrick O. McGowan
    Pages 187-200
  7. Kimberley D. Bruce, Felino R. Cagampang
    Pages 255-288
  8. Frank A. Simmen, Melissa E. Heard, John Mark P. Pabona, Lorenzo M. Fernandes, Charles P. Mercado, Rosalia C. M. Simmen
    Pages 289-305
  9. Katharine C. Pike, Liesbeth Duijts
    Pages 335-354
  10. Paul Cordero, Jiawei Li, Jonathan L. Temple, Vi Nguyen, Jude A. Oben
    Pages 355-368
  11. Erika Isolauri, Samuli Rautava, Maria Carmen Collado, Seppo Salminen
    Pages 369-389

About this book


In this book, leading figures in the field of Developmental Origins of Health and Disease provide up-to-date information from human clinical trials, cohorts, and animal physiology experiments to reveal the interdependence between parental obesity and health of the offspring. Obesity of the mother and father produces obesity in their offspring, so we are caught up in an intergenerational cycle, which means that even our children’s future health is in peril. This book gives a timely and much-needed synthesis of the mechanisms, potential targets of future interventions, and the challenges that need to be overcome in order to break the intergenerational cycle of obesity. This has profound implications for the way in which scientific, clinical and health policy activities are to be directed in order to combat the so-called epidemic of obesity, as well as diabetes, cancer and cardiovascular disease. The book will be of interest to students, clinicians, researchers and health policy makers who are either seeking an introduction to the area of Developmental Origins of Health and Disease or have a specific interest in the pathogenesis of obesity.


Maternal obesity Adipogenesis Periconceptional overnutrition Cardiometabolic risk Epigenetics Offspring metabolic health Postnatal offspring physiology Developmental programming

Editors and affiliations

  • Lucy R. Green
    • 1
  • Robert L. Hester
    • 2
  1. 1.Institute of Developmental SciencesUniversity of SouthamptonSouthamptonUnited Kingdom
  2. 2.Medical CenterThe University of MississippiJacksonUSA

Bibliographic information