Analytical Techniques in the Pharmaceutical Sciences

  • Anette Müllertz
  • Yvonne Perrie
  • Thomas Rades

Part of the Advances in Delivery Science and Technology book series (ADST)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Spectroscopic and Spectrometric Techniques

    1. Front Matter
      Pages 1-1
    2. Jesper Østergaard
      Pages 3-27
    3. Gabriele Reich
      Pages 61-138
    4. Keith C. Gordon, Sara J. Fraser-Miller
      Pages 139-169
    5. Søren Vrønning Hoffmann, Mathias Fano, Marco van de Weert
      Pages 223-251
    6. Ulrike Leurs, Ulrik H. Mistarz, Kasper D. Rand
      Pages 253-289
  3. Diffractometric Techniques

  4. Thermal Techniques

    1. Front Matter
      Pages 361-361
    2. Sheng Qi
      Pages 363-387
    3. S. Gaisford
      Pages 389-409
  5. Separation Techniques

    1. Front Matter
      Pages 411-411
    2. Steen Honore Hansen
      Pages 413-437
  6. Imaging Techniques

    1. Front Matter
      Pages 489-489
    2. Heike Bunjes, Judith Kuntsche
      Pages 491-522
    3. Sara J. Fraser-Miller, Jukka Saarinen, Clare J. Strachan
      Pages 523-589
    4. Ivan M. Kempson, Clive A. Prestidge
      Pages 629-647
    5. Dimitrios A. Lamprou, James R. Smith
      Pages 649-674
  7. Techniques to Characterize Particles

    1. Front Matter
      Pages 675-675
    2. Elisabeth Kastner, Yvonne Perrie
      Pages 677-699
    3. Regina Scherließ
      Pages 701-715
  8. Rheological Techniques

    1. Front Matter
      Pages 717-717
    2. Johanna Aho, Søren Hvidt, Stefania Baldursdottir
      Pages 719-750
  9. Release and Uptake Testing Techniques

    1. Front Matter
      Pages 751-751
    2. Ragna Berthelsen, Anette Müllertz, Thomas Rades
      Pages 753-771
    3. Ragna Berthelsen, Philip Sassene, Thomas Rades, Anette Müllertz
      Pages 773-790
    4. Carsten Uhd Nielsen, Birger Brodin
      Pages 791-822
  10. Back Matter
    Pages 823-838

About this book


The aim of this book is to present a range of analytical methods that can be used in formulation design and development and focus on how these systems can be applied to understand formulation components and the dosage form these build. To effectively design and exploit drug delivery systems, the underlying characteristic of a dosage form must be understood--from the characteristics of the individual formulation components, to how they act and interact within the formulation, and finally, to how this formulation responds in different biological environments. To achieve this, there is a wide range of analytical techniques that can be adopted to understand and elucidate the mechanics of drug delivery and drug formulation. Such methods include e.g. spectroscopic analysis, diffractometric analysis, thermal investigations, surface analytical techniques, particle size analysis, rheological techniques, methods to characterize drug stability and release, and biological analysis in appropriate cell and animal models. Whilst each of these methods can encompass a full research area in their own right, formulation scientists must be able to effectively apply these methods to the delivery system they are considering. 

The information in this book is designed to support researchers in their ability to fully characterize and analyze a range of delivery systems, using an appropriate selection of analytical techniques. Due to its consideration of regulatory approval, this book will also be suitable for industrial researchers both at early stage up to pre-clinical research.


analysis imaging rheology spectroscopy drug discovery diffractometric

Editors and affiliations

  • Anette Müllertz
    • 1
  • Yvonne Perrie
    • 2
  • Thomas Rades
    • 3
  1. 1.Bioneer: FARMA Department of PharmacyUniversity of CopenhagenCopenhagen ØDenmark
  2. 2.Strathclyde Institute of Pharmacy and Biomedical SciencesGlasgowSeychelles
  3. 3.Department of PharmacyUniversity of CopenhagenCopenhagen ØDenmark

Bibliographic information