Tumor Angiogenesis Assays

Methods and Protocols

  • Domenico Ribatti

Part of the Methods in Molecular Biology book series (MIMB, volume 1464)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Ruslan Hlushchuk, Sébastien Barré, Valentin Djonov
    Pages 13-24
  3. Karma Z. Salem, Michele Moschetta, Antonio Sacco, Luisa Imberti, Giuseppe Rossi, Irene M. Ghobrial et al.
    Pages 25-34
  4. Diana M. Sánchez-Palencia, Alex Bigger-Allen, Magali Saint-Geniez, Joseph F. Arboleda-Velásquez, Patricia A. D’Amore
    Pages 35-47
  5. Stefania Orecchioni, Francesco Bertolini
    Pages 49-62
  6. Alfred C. Aplin, Roberto F. Nicosia
    Pages 63-72
  7. Mohammad S. Azimi, Michelle Lacey, Debasis Mondal, Walter L. Murfee
    Pages 85-95
  8. Xiaowen Chen, Dafne Gays, Massimo M. Santoro
    Pages 107-114
  9. Ann L. B. Seynhaeve, Timo L. M. ten Hagen
    Pages 115-127
  10. Alessandra Decio, Raffaella Giavazzi
    Pages 139-149
  11. Ruben Bill, Gerhard Christofori
    Pages 151-161
  12. Clarissa Gillmann, Tobias Bäuerle
    Pages 163-173
  13. Stefano Indraccolo, Stefan Walenta, Wolfgang Mueller-Klieser
    Pages 175-184
  14. Mahtab Bahramsoltani, Ward De Spiegelaere
    Pages 185-191
  15. Back Matter
    Pages 193-194

About this book


This volume aims to provide a range of methods and protocols for studying tumor angiogenesis in vitro and in vivo to reflect advances in the field. The chapters in this book cover topics such as: morphological aspects of tumor angiogenesis, aortic ring assay and its use for the study of tumor angiogenesis, ex vivo tissue culture model for anti-angiogenic drug testing, transgenic zebrafish, orthotopic models of ovarian cancer, and uncovering metabolic effects of anti-angiogenic therapy in tumors by induced metabolic bioluminescence imaging. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting edge and thorough, Tumor Angiogenesis Assays: Methods and Protocols is a valuable resource for anyone interested in tumor angiogenesis assay research.


angiogenesis-dependent angiogenic switch blood vessels tumor tissue proliferation permeability perfusion in vitro assays in vivo assays

Editors and affiliations

  • Domenico Ribatti
    • 1
  1. 1.Neurosciences and Sensory OrgansUniversity of Bari,School of Med Dept of Basic Med SciBariItaly

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2016
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-3997-8
  • Online ISBN 978-1-4939-3999-2
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site