Chromosome Architecture

Methods and Protocols

  • Mark C. Leake

Part of the Methods in Molecular Biology book series (MIMB, volume 1431)

Table of contents

  1. Front Matter
    Pages i-x
  2. Mark C. Leake
    Pages 1-3
  3. Alice L. B. Pyne, Bart W. Hoogenboom
    Pages 47-60
  4. Christian Lesterlin, Nelly Duabrry
    Pages 61-72
  5. Stephen J. Cross, Claire E. Brown, Christoph G. Baumann
    Pages 73-90
  6. Alan Koh, Heath Murray
    Pages 91-108
  7. Michelle Hawkins, John Atkinson, Peter McGlynn
    Pages 151-159
  8. Avelino Javer, Marco Cosentino Lagomarsino, Pietro Cicuta
    Pages 161-173
  9. Rosa Morra, Tomas Fessl, Yuchong Wang, Erika J. Mancini, Roman Tuma
    Pages 175-193
  10. Srinjan Basu, Yi Lei Tan, Edward J. R. Taylor, Ernest D. Laue, Steven F. Lee
    Pages 235-263
  11. Xindan Wang, Paula Montero Llopis
    Pages 275-287
  12. Back Matter
    Pages 289-290

About this book


This volume details a valuable collection of protocols and reviews, such as emerging experimental and theoretical approaches. These approaches have resulted in a substantial improvement in the understanding of chromosome architecture. Chromosome Architecture: Methods and Protocols guides readers through cutting-edge interdisciplinary methods which allow for an understanding of architecture of chromosomes with exceptionally enhanced resolution, both in terms of space and time. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Chromosome Architecture: Methods and Protocols aims to ensure successful results in the further study of this vital field.


dynamic architecture chromosomes molecular length scale single-molecule methods super-resolution techniques biophysics

Editors and affiliations

  • Mark C. Leake
    • 1
  1. 1.Biological Physical Sciences InstitUniversity of YorkYorkUnited Kingdom

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2016
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-3629-8
  • Online ISBN 978-1-4939-3631-1
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site