Systems Medicine

  • Ulf Schmitz
  • Olaf Wolkenhauer

Part of the Methods in Molecular Biology book series (MIMB, volume 1386)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. A Road Map Toward Systems Medicine

    1. Front Matter
      Pages 1-1
    2. Marc Kirschner
      Pages 3-15
    3. Antoine H. C. van Kampen, Perry D. Moerland
      Pages 17-41
    4. Mansoor Saqi, Johann Pellet, Irina Roznovat, Alexander Mazein, Stéphane Ballereau, Bertrand De Meulder et al.
      Pages 43-60
    5. Peter D. Caie, David J. Harrison
      Pages 61-72
    6. Lars Kuepfer, Andreas Schuppert
      Pages 87-104
  3. Opinions and Persepectives

    1. Front Matter
      Pages 105-105
    2. Ruth Bowness
      Pages 107-118
    3. Bernd Schmeck, Wilhelm Bertrams, Xin Lai, Julio Vera
      Pages 119-133
    4. Martin Eberhardt, Xin Lai, Namrata Tomar, Shailendra Gupta, Bernd Schmeck, Alexander Steinkasserer et al.
      Pages 135-179
    5. Silvio Parodi, Giuseppe Riccardi, Nicoletta Castagnino, Lorenzo Tortolina, Massimo Maffei, Gabriele Zoppoli et al.
      Pages 181-219
    6. Marek Ostaszewski, Alexander Skupin, Rudi Balling
      Pages 221-250
  4. Systems Medicine Projects and Case Studies

    1. Front Matter
      Pages 251-251
    2. Raheleh Amirkhah, Ali Farazmand, Olaf Wolkenhauer, Ulf Schmitz
      Pages 305-330
  5. Tools and Methodologies

    1. Front Matter
      Pages 351-351
    2. Sonja Strunz, Olaf Wolkenhauer, Alberto de la Fuente
      Pages 353-374
    3. Alexandru Mizeranschi, Derek Groen, Joris Borgdorff, Alfons G. Hoekstra, Bastien Chopard, Werner Dubitzky
      Pages 375-404
    4. Adam L. MacLean, Heather A. Harrington, Michael P. H. Stumpf, Helen M. Byrne
      Pages 405-439
    5. Brett G. Olivier, Maciej J. Swat, Martijn J. Moné
      Pages 441-463
  6. Back Matter
    Pages 465-478

About this book


This volume guides readers through the field of systems medicine by defining the terminology, and describing how established computational methods form bioinformatics and systems biology can be taken forward to an integrative systems medicine approach. Chapters provide an outlook on the role that systems medicine may or should play in various medical fields, and describe different facets of the systems medicine approach in action. Ultimately it introduces tools, resources and methodologies from bioinformatics and systems biology, and how to apply these in a systems medicine project. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, and discuss experimental and computational approaches, methods,  and tools that should be considered for a successful systems medicine project. Systems Medicine aims to motivate and provide guidance for collaborations across disciplines to tackle today's challenges related to human health and well-being.


bioinformatic chronic pulmonary disease human metabolism immune-related diseases lung diseases neurology regenerative stem cell systems medicine wet lab experiments

Editors and affiliations

  • Ulf Schmitz
    • 1
  • Olaf Wolkenhauer
    • 2
  1. 1.Dept of Systems Biology & BioinformaticsUniversity of RostockRostockGermany
  2. 2.Dept of Systems Biology & BioinformaticsUniversity of RostockRostockGermany

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2016
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-3282-5
  • Online ISBN 978-1-4939-3283-2
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site