Clinical Applications of Mass Spectrometry in Drug Analysis

Methods and Protocols

  • Uttam Garg

Part of the Methods in Molecular Biology book series (MIMB, volume 1383)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Stephanie J. Marin, Gwendolyn A. McMillin
    Pages 59-68
  3. Shuang Deng, Michael Kiscoan, Clint Frazee, Susan Abdel-Rahman, Jignesh Dalal, Uttam Garg
    Pages 79-87
  4. Ada Munar, Clint Frazee, Bridgette Jones, Uttam Garg
    Pages 115-120
  5. Bheemraj Ramoo, Melissa Funke, Clint Frazee, Uttam Garg
    Pages 125-131
  6. Alan H. B. Wu, Jennifer Colby
    Pages 153-166
  7. Geoffrey S. Rule, Alan L. Rockwood, Kamisha L. Johnson-Davis
    Pages 195-203
  8. Judy Peat, Clint Frazee, Gregory Kearns, Uttam Garg
    Pages 205-211
  9. Ryan C. Schofield, Lakshmi V. Ramanathan, Kazunori Murata, Martin Fleisher, Melissa S. Pessin, Dean C. Carlow
    Pages 213-222
  10. Back Matter
    Pages 271-272

About this book


This volume describes methods and protocols for a number of drugs and toxins in a stepwise manner. Chapters in the book cover a wide array of topics such as: quantitation of Flecainide, Mexiletine, Propafenone, and Amiodarone in Serum or Plasma; quantitation of total Buprenorphine and Norbuprenorphine in Meconium; quantitation or Carisoprodol and Meprobamate in Urine; and quantitation of Tricyclic Antidepressants in Serum. Each chapter contains a brief introduction to the topic, clinical utility of the analyte(s), and useful notes to help laboratorians easily reproduce the protocols discussed. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and thorough, Clinical Applications of Mass Spectrometry in Drug Analysis: Methods and Protocols, is a great resource for laboratorians who are already using mass spectrometry or thinking of introducing this technology to their laboratories.


Antibodies Drug and Toxins Analyses Mass Spectrometry (MS) Multi-Component Analysis Toxin analysis

Editors and affiliations

  • Uttam Garg
    • 1
  1. 1.Dept of Pathology & Lab MedicineChildren's Mercy Hospitals & ClinicsKansas CityUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2016
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-3251-1
  • Online ISBN 978-1-4939-3252-8
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site