Genomic Elements in Health, Disease and Evolution

Junk DNA

  • Kyriacos Felekkis
  • Konstantinos Voskarides

Table of contents

  1. Front Matter
    Pages i-xi
  2. Gregory Papagregoriou
    Pages 17-46
  3. Monika Gullerova
    Pages 83-108
  4. Ioannis S. Vizirianakis, Elsa P. Amanatiadou, Sotirios S. Tezias
    Pages 109-127
  5. Carolina Sismani, Costas Koufaris, Konstantinos Voskarides
    Pages 129-154
  6. Vasiliki A. Galani, Sofia Markoula, Leandros Lazaros, Paris Ladias, Ioannis Georgiou
    Pages 155-193
  7. María Dolores Molina-Sánchez, Rafael Nisa-Martínez, Fernando M. García-Rodríguez, Francisco Martínez-Abarca, Nicolás Toro
    Pages 195-219
  8. Thian Thian Beh, Paul Kalitsis
    Pages 221-245
  9. Penelope Kroustallaki, Sarantis Gagos
    Pages 247-283
  10. Michalis Hadjithomas
    Pages 297-311
  11. Back Matter
    Pages 313-315

About this book

Introduction

This book provides a thorough review of various non-coding genomic elements and discusses in depth their role in health, disease and evolution. It begins with an exploration of non-coding RNA molecules miRNAs, piRNAs, LncRNAs and transposable elements as these moieties dominate the scientific literature the last ten years. The second part of the book discusses copy number variation regions, mini and micro satellites, and proximal and distal elements of the genome.  The last section of the book focuses on the review of well-known non-coding regions of the genome, introns, centromeres and telomeres, but enriched with newly discovered functions.  As the vast amount of data in regards to these elements is attributed to a great degree to the growing technology in the field of biomedicine, the last chapter of the book discusses the latest development in the field of Next Generation Sequence and the potential applications of this technology in the study of non-coding regions of the genome. This new volume provides an in depth background on ‘junk DNA’ and helps set the stage for future research, and is an essential tool for those in the field.

Keywords

copy number variations miRNA genes miRNA targets natural selection non-coding sequences transposons

Editors and affiliations

  • Kyriacos Felekkis
    • 1
  • Konstantinos Voskarides
    • 2
  1. 1.Department of Life and Health Sciences and University of Nicosia Medical School, University of NicosiaNicosiaCyprus
  2. 2.Department of Biological Sciences, Molecular Medicine Research Center, University of CyprusNicosiaCyprus

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4939-3070-8
  • Copyright Information Springer Science+Business Media New York 2015
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4939-3069-2
  • Online ISBN 978-1-4939-3070-8
  • About this book