DNA-Protein Interactions

Principles and Protocols

  • Benoît P. Leblanc
  • Sébastien Rodrigue

Part of the Methods in Molecular Biology book series (MIMB, volume 1334)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Dominic Poulin-Laprade, Vincent Burrus
    Pages 1-15
  3. Benoît P. Leblanc, Tom Moss
    Pages 17-27
  4. Régen Drouin, Nathalie Bastien, Jean-François Millau, François Vigneault, Isabelle Paradis
    Pages 41-84
  5. Yinshan Jia, Linda Nagore, Harry Jarrett
    Pages 85-99
  6. Julien Boudreault, D. Cibran Perez-Gonzalez, J. Carlos Penedo, Daniel A. Lafontaine
    Pages 101-107
  7. Adrien Chauvier, Daniel A. Lafontaine
    Pages 109-114
  8. Simon Blouin, Timothy D. Craggs, Daniel A. Lafontaine, J. Carlos Penedo
    Pages 115-141
  9. David J. Clark, Benoît P. Leblanc
    Pages 161-172
  10. Mayra Furlan-Magaril, Félix Recillas-Targa
    Pages 205-218
  11. Virginia Babl, Ulrike Stöckl, Herbert Tschochner, Philipp Milkereit, Joachim Griesenbeck
    Pages 219-232
  12. Frédéric Grenier, Jean-François Lucier, Sébastien Rodrigue
    Pages 233-244
  13. Mylène Brunelle, Charles Coulombe, Christian Poitras, Marc-Antoine Robert, Alexei Nordell Markovits, François Robert et al.
    Pages 273-298
  14. Garry Scarlett, Giuliano Siligardi, Geoffrey G. Kneale
    Pages 299-312
  15. Back Matter
    Pages 345-347

About this book


This fourth edition reflects the most recent technical advances in DNA-protein interaction research. With fully updated chapters that describe techniques proven by their continuous value, the volume also many new chapters have been added that mostly deal with larger-scale experiments, reflecting recent advances in "big biology", combining to offer a very useful compendium of protocols allowing readers to delve into the intricacies of protein-DNA interaction at levels ranging from the very small (as in the case of single-molecule FRET) to the very complex (as with circular chromatin conformation capture, or 4C). Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and up-to-date, DNA-Protein Interactions: Principles and Protocols, Fourth Edition will aid researchers in continuing the incredible progress made in this vital area of study.


Chromatin immunoprecipitation Circular chromatin conformation capture (4C) Gene expression regulation Massive parallel sequencing Personal genomics Sequence specificity Single-molecule FRET

Editors and affiliations

  • Benoît P. Leblanc
    • 1
  • Sébastien Rodrigue
    • 2
  1. 1.Département de Biologie, Faculté des SciencesUniversité de SherbrookeSherbrookeCanada
  2. 2.Département de Biologie, Faculté des SciencesUniversité de SherbrookeSherbrookeCanada

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2015
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-2876-7
  • Online ISBN 978-1-4939-2877-4
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site