Table of contents
Systems Biology of Multifactorial Diseases: Alzheimer’s Disease
Alzheimer’s Disease: Main Underlying Pathways and Networks
Comprehensive Disease Models Recapitulating Alzheimer’s Disease Features: From Cellular Models to Human
Experimental Systems Biology: Next Generation Molecular and High-Throughput Methods for the Study of Disease Susceptibility and Networks Dynamics Interplay in Complex Diseases
Computational Systems Biology, Network Biology: Next Generation Computational and Integrative Network Biology Approaches for the Study of Modules, Network Dynamics, and Their Interplay in Complex Diseases
Systems Biology of Alzheimer’s Disease in Practice: From Systems Biology to Early Diagnostics and Systems Medicine
About this book
Alzheimer’s disease (AD) and many other neurodegenerative disorders are multifactorial in nature, involving a combination of genomic, epigenomic, network dynamic, and environmental factors. A proper investigation requires new integrative Systems Biology approaches, at both the experimental and computational level. The interplay of disease mechanisms and homeostatic networks will underlie the time of onset and rate of progression of the disease.
This book addresses such an integrated approach to AD. It aims to present Systems Biology, including both experimental and computational approaches, as a new strategy for the study of AD and other multifactorial diseases, with the hope that the results will translate into more effective diagnosis and treatment, as well as improved public health policies.
Written for the highly successful Methods in Molecular Biology series, practical and cutting-edge, Systems Biology of Alzheimer’s Disease is intended for post-graduate students, post-doctoral researchers, and experts in different fields with an interest in comprehensive Systems Biology strategies applicable to AD and other complex multifactorial diseases (including other neurodegenerative diseases and cancers). This book aims to complement other excellent volumes and monographs on AD that cover fundamental, physiological, or medical aspects of the disease.
Editors and affiliations
- DOI https://doi.org/10.1007/978-1-4939-2627-5
- Copyright Information Springer Science+Business Media New York 2016
- Publisher Name Humana Press, New York, NY
- eBook Packages Springer Protocols
- Print ISBN 978-1-4939-2626-8
- Online ISBN 978-1-4939-2627-5
- Series Print ISSN 1064-3745
- Series Online ISSN 1940-6029
- Buy this book on publisher's site