Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites, Volume 2

  • Susanne Zeilinger
  • Juan-Francisco Martín
  • Carlos García-Estrada

Part of the Fungal Biology book series (FUNGBIO)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Susanne Zeilinger, Carlos García-Estrada, Juan-Francisco Martín
    Pages 1-12
  3. Benjamin P. Knox, Nancy P. Keller
    Pages 13-28
  4. Ming-Yueh Wu, Jae-Hyuk Yu
    Pages 29-42
  5. Grayson T. Wawrzyn, Mark A. Held, Sarah E. Bloch, Claudia Schmidt-Dannert
    Pages 43-65
  6. Bernhard Kluger, Sylvia Lehner, Rainer Schuhmacher
    Pages 81-101
  7. Jens C. Frisvad
    Pages 103-121
  8. Fernanda O. Chagas, Andrés Mauricio Caraballo-Rodriguez, Mônica T. Pupo
    Pages 123-176
  9. Gerhard Adam, Gerlinde Wiesenberger, Ulrich Güldener
    Pages 199-233
  10. Back Matter
    Pages 253-256

About this book


This book continues the exploration of fungal secondary metabolism and underlying genetics initiated in the first volume, adding analysis of regulatory key players and epigenetic control of their biosynthesis, genomics- and metabolomics-guided approaches. This work unearths the potential of fungi as resources of novel biologically active substances, the use of secondary metabolite profiles in fungal chemotaxonomy, less exploited substances and their producers, and the biological roles of secondary metabolites in organismic interactions.


Fungal secondary metabolites significantly impact mankind, comprising substances that contribute to human well-being such as antibiotics, antivirals, immunosuppressives, antitumor and anticholesterolemic agents. These metabolites also comprise toxins that act as virulence factors in their respective hosts, causing health problems by contaminating our food and indoor environment. For the use of beneficial substances in medicine and pharmaceutical industry and the risk reduction of fungal metabolites with adverse health effects, a detailed knowledge and understanding of fungal secondary metabolism is essential. The recent emergence of high-throughput “omics” techniques constitutes an important step in this regard and will further significantly contribute to the discovery of novel fungal metabolites.


Fungal Biology Fungal Development Fungal genomics Secondary Metabolism metabolomics of fungi

Editors and affiliations

  • Susanne Zeilinger
    • 1
  • Juan-Francisco Martín
    • 2
  • Carlos García-Estrada
    • 3
  1. 1.Institute of Chemical EngineeringVienna University of TechnologyViennaAustria
  2. 2.Department of Molecular BiologyUniversity of LeónLeónSpain
  3. 3.Biomedicine and Biopharma Area (INBIOTEC)Instituto de Biotecnología de LeónLeónSpain

Bibliographic information