Methods and Protocols

  • Jacob T. Bjerrum

Part of the Methods in Molecular Biology book series (MIMB, volume 1277)

Table of contents

  1. Front Matter
    Pages i-x
  2. Gwénaëlle Le Gall
    Pages 29-36
  3. Guro F. Giskeødegård, Maria D. Cao, Tone F. Bathen
    Pages 37-50
  4. Xinjie Zhao, Lina Zhou, Peiyuan Yin, Guowang Xu
    Pages 61-73
  5. Abdul-Hamid M. Emwas, Zeyad A. Al-Talla, Najeh M. Kharbatia
    Pages 75-90
  6. Abdul-Hamid M. Emwas, Zeyad A. Al-Talla, Yang Yang, Najeh M. Kharbatia
    Pages 91-112
  7. Masataka Wakayama, Akiyoshi Hirayama, Tomoyoshi Soga
    Pages 113-122
  8. Riyas Vettukattil
    Pages 123-136
  9. Mattias Rantalainen
    Pages 147-159
  10. Pranov Ramana, Erwin Adams, Patrick Augustijns, Ann Van Schepdael
    Pages 195-207
  11. Liang Zhao, Thomas Hartung
    Pages 209-231
  12. Lucy C. Hicks, Simon J. L. Ralphs, Horace R. T. Williams
    Pages 233-244
  13. Vicky De Preter
    Pages 245-255
  14. Back Matter
    Pages 257-259

About this book


This volume on metabonomics provides detailed information on the procedures involved in nuclear magnetic resonance (NMR) spectroscopy, gas chromatography-mass spectrometry (GS-MS), liquid chromatography-mass spectrometry (LC-MS), and capillary electrophoresis-mass spectrometry (CE-MS). Chapters focus on technologies and chemometrics,  generation of metabonomics data, extraction of meaningful information from data,  drug development, toxicology, diagnostics,  and describing metabonomics as an essential part of systems biology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls


capillary electrophoresis-mass spectrometry (CE-MS) chemometrics drug development gas chromatography-mass spectrometry (GS-MS) human metabonomics liquid chromatography-mass spectrometry (LC-MS) metabonomics data nuclear magnetic resonance (NMR) spectroscopy

Editors and affiliations

  • Jacob T. Bjerrum
    • 1
  1. 1.Department of Gastroenterology, Medical SectionHerlev Hospital, University of CopenhagenCopenhagenDenmark

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2015
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-2376-2
  • Online ISBN 978-1-4939-2377-9
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site