Mitochondrial Medicine

Volume I, Probing Mitochondrial Function

  • Volkmar Weissig
  • Marvin Edeas

Part of the Methods in Molecular Biology book series (MIMB, volume 1264)

Table of contents

  1. Front Matter
    Pages i-xxv
  2. Stefan Lehr, Sonja Hartwig, Jorg Kotzka
    Pages 1-8
  3. Sonja Hartwig, Jorg Kotzka, Stefan Lehr
    Pages 9-23
  4. Ted Pham, Katayoun Zand, Douglas Wallace, Peter Burke
    Pages 35-46
  5. Venkata Suresh Vajrala, Emmanuel Suraniti, Bertrand Goudeau, Neso Sojic, Stéphane Arbault
    Pages 47-58
  6. Brendan A. I. Payne, Kristian Gardner, Jonathan Coxhead, Patrick F. Chinnery
    Pages 59-66
  7. Brendan A. I. Payne, Lynsey Cree, Patrick F. Chinnery
    Pages 67-76
  8. Wilber Quispe-Tintaya, Ryan R. White, Vasily N. Popov, Jan Vijg, Alexander Y. Maslov
    Pages 89-95
  9. Wei Wang, Ying Esbensen, Katja Scheffler, Lars Eide
    Pages 97-106
  10. Geng Wang, Eriko Shimada, Mahta Nili, Carla M. Koehler, Michael A. Teitell
    Pages 107-116
  11. Liping Yu, Brian D. Fink, William I. Sivitz
    Pages 149-159
  12. Marleen Forkink, Peter H. G. M. Willems, Werner J. H. Koopman, Sander Grefte
    Pages 161-169
  13. Julia Horilova, Hauke Studier, Zuzana Nadova, Pavol Miskovsky, Dusan Chorvat Jr., Alzbeta Marcek Chorvatova
    Pages 183-193

About this book

Introduction

This expert volume covers an interdisciplinary and rapidly growing area of biomedical research comprising genetic, biochemical, pathological, and clinical studies aimed at the diagnosis and therapy of human diseases which are either caused by or associated with mitochondrial dysfunction. It dedicates itself to showcasing the tremendous efforts and the progress that has been made over the last decades in developing techniques and protocols for probing, imaging, and manipulating mitochondrial functions. Mitochondrial Medicine: Methods and Protocols, Volume I: Probing Mitochondrial Function focuses on methods being used for the assessment of mitochondrial function under physiological conditions as well as in healthy isolated mitochondria. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Comprehensive and practical, Mitochondrial Medicine: Methods and Protocols provides an essential source of know-how and inspiration to all researchers who are fascinated by this tiny organelle that seems so clearly to control the life and death of a single cell and whole organisms alike.

Keywords

Apoptosis Deep sequencing Human mitochondrial DNA Mitochondria isolation Mitochondria-related diseases Next generation sequencing mtDNA

Editors and affiliations

  • Volkmar Weissig
    • 1
  • Marvin Edeas
    • 2
  1. 1.Midwestern UniversityGlendaleUSA
  2. 2.ISANHParisFrance

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4939-2257-4
  • Copyright Information Springer Science+Business Media New York 2015
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-2256-7
  • Online ISBN 978-1-4939-2257-4
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • About this book