Chemistry and Biology

  • Kuberan Balagurunathan
  • Hiroshi Nakato
  • Umesh R. Desai

Part of the Methods in Molecular Biology book series (MIMB, volume 1229)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Structure

    1. Front Matter
      Pages 1-1
    2. Chien-Fu Liang, Heung Sik Hahm, Peter H. Seeberger
      Pages 3-10
    3. April Joice, Karthik Raman, Caitlin Mencio, Maritza V. Quintero, Spencer Brown, Thao Kim Nu Nguyen et al.
      Pages 11-19
    4. Karthik Raman, Balagurunathan Kuberan, Sailaja Arungundram
      Pages 31-36
    5. Xylophone V. Victor, Vy M. Tran, Balagurunathan Kuberan, Thao Kim Nu Nguyen
      Pages 43-48
    6. Rami A. Al-Horani, Rajesh Karuturi, Stephen Verespy III, Umesh R. Desai
      Pages 49-67
    7. Caitlin Mencio, Dinesh R. Garud, Balagurunathan Kuberan, Mamoru Koketsu
      Pages 69-78
    8. Md. Ferdous Anower-E-Khuda, Koji Kimata
      Pages 95-103
    9. Miroslaw Lech, Ishan Capila, Ganesh V. Kaundinya
      Pages 119-128
    10. Athanasia P. Asimakopoulou, Christina Malavaki, Nikolaos A. Afratis, Achilleas D. Theocharis, Fotini N. Lamari, Nikos K. Karamanos
      Pages 129-141
    11. Evgenia Karousou, Athanasia P. Asimakopoulou, Vassiliki Zafeiropoulou, Manuela Viola, Luca Monti, Antonio Rossi et al.
      Pages 143-159
    12. Consuelo N. Beecher, Cynthia K. Larive
      Pages 173-187
    13. Anders Dagälv, Anders Lundequist, Beata Filipek-Górniok, Tabea Dierker, Inger Eriksson, Lena Kjellén
      Pages 189-200
    14. Davide Vigetti, Evgenia Karousou, Manuela Viola, Alberto Passi
      Pages 201-208
    15. Ponnusamy Babu, Xylophone V. Victor, Karthik Raman, Balagurunathan Kuberan
      Pages 209-219
    16. Hadi Tavakoli Nia, Christine Ortiz, Alan Grodzinsky
      Pages 221-237
    17. Rebecca J. Holley, Raymond A. Smith, Els M. A. van de Westerlo, Claire E. Pickford, C. L. R. Merry, Toin H. van Kuppevelt
      Pages 239-251
  3. Functions

    1. Front Matter
      Pages 269-269
    2. Nehru Viji Sankaranarayanan, Aurijit Sarkar, Umesh R. Desai, Philip D. Mosier
      Pages 289-314
    3. Prem Raj B. Joseph, Krishna Mohan Poluri, Krishna Mohan Sepuru, Krishna Rajarathnam
      Pages 325-333
    4. Rio S. Boothello, Rami A. Al-Horani, Umesh R. Desai
      Pages 335-353
    5. Marika Bogdani, Charmaine Simeonovic, Nadine Nagy, Pamela Y. Johnson, Christina K. Chan, Thomas N. Wight
      Pages 413-430
    6. Cheryl M. Ethen, Miranda Machacek, Brittany Prather, Timothy Tatge, Haixiao Yu, Zhengliang L. Wu
      Pages 431-441
    7. Mauricio Cortes, Leslie K. Cortes, Nancy B. Schwartz
      Pages 443-455
    8. Tony W. Hsiao, Vimal P. Swarup, Colin D. Eichinger, Vladimir Hlady
      Pages 457-467
    9. David Gailani, Qiufang Cheng, Ivan S. Ivanov
      Pages 483-496
    10. Masahiko Takemura, Hiroshi Nakato
      Pages 497-505
    11. Anna Wade, Jane R. Engler, Vy M. Tran, Joanna J. Phillips
      Pages 507-516
    12. Mausam Kalita, Maritza V. Quintero, Karthik Raman, Vy M. Tran, Balagurunathan Kuberan
      Pages 517-528
    13. Nirmita Patel, Somesh Baranwal, Bhaumik B. Patel
      Pages 529-541
    14. Mark E. Lauer, Jacqueline Loftis, Carol de la Motte, Vincent C. Hascall
      Pages 543-548
    15. Hong Qiu, Wenyuan Xiao, Jingwen Yue, Lianchun Wang
      Pages 549-555
    16. James A. Vassie, John M. Whitelock, Megan S. Lord
      Pages 557-565
    17. Akiko Jinno, Pyong Woo Park
      Pages 567-585
    18. Simon J. Foulcer, Anthony J. Day, Suneel S. Apte
      Pages 587-604

About this book


 Glycosaminoglycans: Chemistry and Biology emphasizes several areas of glycosaminoglycan research especially analysis and application of GAGs using a variety of approaches.  Chapters focus on chemical and enzymatic synthesis of GAGs for therapeutic purposes; biophysical and biochemical methods for studying GAG-protein interactions; molecular approaches for modulating and defining GAG biosynthesis; informatics approaches for deciphering GAG code; computational approaches for establishing specific and/or non-specific interactions and genetic and biochemical tools for manipulating/visualizing glycosaminoglycan expression and studying their functions in a variety of model organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

 Authoritative and practical, Glycosaminoglycans: Chemistry and Biology serves as a valuable manual for cutting edge methodologies and practical tips to overcome any obstacles with experimentation pertaining to chemistry and biology of glycosaminoglycans.


GAG-protein interactions Glycosaminoglycan biopolymers defining GAG biosynthesis enzymatic synthesis of GAGs genetic and biochemical tools manipulating expression model organisms visualizing glycosaminoglycan expression

Editors and affiliations

  • Kuberan Balagurunathan
    • 1
  • Hiroshi Nakato
    • 2
  • Umesh R. Desai
    • 3
  1. 1.Department of Medicinal ChemistryUniversity of UtahSalt Lake CityUSA
  2. 2.Department of Genetics, Cell Biology and DevelopmentThe University of MinnesotaMinneapolisUSA
  3. 3.Department of Medicinal ChemistryVirginia Commonwealth UniversityRichmondUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2015
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-1713-6
  • Online ISBN 978-1-4939-1714-3
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site