Innate DNA and RNA Recognition

Methods and Protocols

  • Hans-Joachim Anders
  • Adriana Migliorini

Part of the Methods in Molecular Biology book series (MIMB, volume 1169)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Analysis of Viral Nucleic Acid Sensing In-Silico and In-Vitro

    1. Front Matter
      Pages 1-1
    2. Gernot Nees, Andreas Kaufmann, Stefan Bauer
      Pages 3-14
    3. Marion Goldeck, Martin Schlee, Gunther Hartmann, Veit Hornung
      Pages 15-25
    4. Filiz Civril, Karl-Peter Hopfner
      Pages 27-35
    5. Andreas Schmidt, Andreas Linder, Nicolas Linder, Simon Rothenfusser
      Pages 37-44
    6. Jing Gong, Tiandi Wei
      Pages 45-53
    7. Alexander Heiseke, Katharina Eisenächer, Anne Krug
      Pages 55-65
    8. Simone Romoli, Adriana Migliorini
      Pages 77-86
    9. Saskia Ziegler, Isabelle Bekeredjian-Ding
      Pages 87-96
    10. Julia Roider, Thomas Vollbrecht, Rika Draenert
      Pages 97-106
    11. Theresa Kaeuferle, Sabine Bartel, Stefan Dehmel, Susanne Krauss-Etschmann
      Pages 121-130
  3. Analysis of Nucleic Acid Sensing In-Vivo

    1. Front Matter
      Pages 131-131
    2. Amanda A. Watkins, Ramon G. B. Bonegio, Ian R. Rifkin
      Pages 143-158
    3. John M. Hoppe, Volker Vielhauer
      Pages 159-174
    4. Moritz Rapp, David Anz, Max Schnurr
      Pages 175-179
    5. Fanny Matheis, Robert Besch
      Pages 181-192
  4. Back Matter
    Pages 193-195

About this book


Innate DNA and RNA Recognition: Method and Protocols presents validated experimental strategies to dissect nucleic acid sensing in-vitro and in-vivo sources. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.


Authoritative and practical, Innate DNA and RNA Recognition: Method and Protocols provides a resource for immunologists, molecular biologists, virologists, microbiologists, and researchers studying how the innate immune system handles nucleic acids from endogenous or foreign sources.


aberrant activation epigenetic DNA and RNA modifications extracellular nuclear particles immune tolerance innate immune responses innate immune system nucleic acid sensing pathogen pathogen recognition proliferation of auto-reactive lymphocytes tolerogenic autoantigen-presentation

Editors and affiliations

  • Hans-Joachim Anders
    • 1
  • Adriana Migliorini
    • 2
  1. 1.Ludwig Maximilians Universität MünchenMedizinische Klinik und Poliklinik IVMünchenGermany
  2. 2.Helmholtz Zentrum München German ResearcInstitute for Diabetes and RegenerationMunichGermany

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, New York 2014
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-0881-3
  • Online ISBN 978-1-4939-0882-0
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site