Cancer Vaccines

Methods and Protocols

  • Michael J.P. Lawman
  • Patricia D. Lawman

Part of the Methods in Molecular Biology book series (MIMB, volume 1139)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Manipulation and Modification of Immune Cells: Dendritic Cells

    1. Front Matter
      Pages 1-1
    2. Hyun-Ju Lee, Nu-Ri Choi, Manh-Cuong Vo, My-Dung Hoang, Youn-Kyung Lee, Je-Jung Lee
      Pages 17-26
    3. Laura Alaniz, Manglio M. Rizzo, Guillermo Mazzolini
      Pages 27-31
    4. Manglio M. Rizzo, Laura Alaniz, Guillermo Mazzolini
      Pages 41-44
    5. Sumit K. Hira, Deepak Verma, Partha P. Manna
      Pages 45-56
    6. Joseph Senesac, Dmitry Gabrilovich, Samuel Pirruccello, James E. Talmadge
      Pages 97-118
    7. Naoshi Kawamura, Masaru Udagawa, Tomonobu Fujita, Toshiharu Sakurai, Tomonori Yaguchi, Yutaka Kawakami
      Pages 145-153
    8. Roeland Lameris, Famke L. Schneiders, Tanja D. de Gruijl, Hans J. van der Vliet
      Pages 155-165
  3. Manipulation and Modification of Immune Cells: T Lymphocytes and NK Cells

    1. Front Matter
      Pages 167-167
    2. Aaron E. Foster, Xiao-Tong Song
      Pages 169-176
    3. Liza B. John, Tess M. Chee, David E. Gilham, Phillip K. Darcy
      Pages 177-187
    4. Serena K. Perna, Barbara Savoldo, Gianpietro Dotti
      Pages 189-200
    5. Syh-Jae Lin, Pei-Tzu Lee, Ming-Ling Kuo
      Pages 223-229
  4. Manipulation and Modification of Tumor Cells

    1. Front Matter
      Pages 231-231
    2. Eva Lion, Charlotte M. de Winde, Viggo F. I. Van Tendeloo, Evelien L. J. M. Smits
      Pages 233-241
    3. Vijayakumar K. Ramiya, Maya M. Jerald, Patricia D. Lawman, Michael J. P. Lawman
      Pages 243-257
    4. Mohamed R. Akl, Nehad M. Ayoub
      Pages 259-268
    5. Haval Shirwan, Esma S. Yolcu, Rajesh K. Sharma, Hong Zaho, Orlando Grimany-Nuno
      Pages 269-285
  5. Manipulation of Immune/Tumor Interactions

    1. Front Matter
      Pages 287-287
    2. Christian Kleist, Marco Randazzo, Janina Jiga, Peter Terness
      Pages 305-319
    3. Sonia A. Perez, George E. Peoples, Michael Papamichail, Constantin N. Baxevanis
      Pages 321-336
    4. Hidekazu Shirota, Dennis M. Klinman
      Pages 337-344
    5. Rena Morita, Yoshihiko Hirohashi, Munehide Nakatsugawa, Takayuki Kanaseki, Toshihiko Torigoe, Noriyuki Sato
      Pages 345-355
    6. Bing Ni, Zhengcai Jia, Yuzhang Wu
      Pages 357-366
    7. Susana Inoges, Ascensión López Díaz de Cerio, Helena Villanueva, Fernando Pastor, Maurizio Bendandi
      Pages 367-387
  6. Delivery Mechanisms

    1. Front Matter
      Pages 405-405
    2. Paul M. Howley, Kerrilyn R. Diener, John D. Hayball
      Pages 407-427
    3. Yan Wang, Bertrand Toussaint, Audrey Le Gouëllec
      Pages 429-441
    4. Santwana Bhatnagar, Raza Ali Naqvi, Riyasat Ali, D. N. Rao
      Pages 443-452
    5. Vijaya Bharti Joshi, Sean M. Geary, Aliasger K. Salem
      Pages 453-466
    6. Rama P. Kotipatruni, Ganji Purnachandra Nagaraju
      Pages 467-476
  7. The Advances, Challenges, and Future of Cancer Vaccines

    1. Front Matter
      Pages 477-477
    2. Hauke Winter, Bernard A. Fox, Dominik Rüttinger
      Pages 555-564
  8. Back Matter
    Pages 565-569

About this book


Cancer Vaccines: Methods and Protocols explores the manipulation and modification of immune cells, the manipulation and modification of tumor cells, as well as the manipulation of immune/tumor interactions and various delivery mechanisms, with the overall end goal of evoking a tumor-specific response and overcoming the immuno-evasive mechanisms employed by the tumor cells.  This detailed volume also covers the subject of cancer vaccines in a more global sense with its section on the advances, challenges, and future of cancer vaccines.  Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.


Comprehensive and authoritative, Cancer Vaccines: Methods and Protocols aims to help guide researchers toward developing further generations of cancer vaccines that are both safe and efficacious, with the hope that cancer vaccines will be the standard of care in the very near future.


Cancer immunotherapies Delivery mechanisms Dendritic cells Immune cell manipulation Immune system Immunotherapy NK cells T lymphocytes Therapeutic cancer vaccine Tumor cell modification

Editors and affiliations

  • Michael J.P. Lawman
    • 1
  • Patricia D. Lawman
    • 2
  1. 1.Morphogenesis, Inc.TampaUSA
  2. 2.Morphogenesis, Inc.TampaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2014
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-0344-3
  • Online ISBN 978-1-4939-0345-0
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site