Introduction to Drug Metabolism

  • G. Gordon Gibson
  • Paul Skett

Table of contents

  1. Front Matter
    Pages i-xii
  2. G. Gordon Gibson, Paul Skett
    Pages 1-37
  3. G. Gordon Gibson, Paul Skett
    Pages 39-81
  4. G. Gordon Gibson, Paul Skett
    Pages 82-112
  5. G. Gordon Gibson, Paul Skett
    Pages 113-146
  6. G. Gordon Gibson, Paul Skett
    Pages 147-174
  7. G. Gordon Gibson, Paul Skett
    Pages 175-198
  8. G. Gordon Gibson, Paul Skett
    Pages 199-238
  9. G. Gordon Gibson, Paul Skett
    Pages 239-284
  10. Back Matter
    Pages 285-293

About this book


Although the scientific literature on drug metabolism is extensive, it suffers from the disadvantage that the material is diffuse and consists largely of specialist monographs dealing with particular aspects of the subject. In addi­ tion, although there are a few excellent texts on drug metabolism in print, these tend to be earlier publications and hence do not take into account the many recent advances in this area. Our motivations for writing this book therefore arose from the clear need for a recent and cohesive introductory text on this subject, specifically designed to cater for the needs of undergraduate and postgraduate students. Much of the subject matter in this text is derived from various courses on drug metabolism given at the University of Surrey and the University of Glasgow to basic science students in pharmacology, biochemistry, nutrition and nursing studies, to pre-clinical medical students and to under­ graduate and post-graduate students in toxicology. Therefore, it is our inten­ tion that this text will serve as a primer in drug metabolism to a variety of students in the life sciences taking courses in this subject. The term 'drug metabolism' in its broadest sense may be considered as the absorption, distribution, biotransformation and excretion of drugs. To cover all these facets of drug metabolism in a single text is a voluminous task and therefore we have focused primarily on the biotransformation aspects of the subject.


absorption biochemistry drug kinetics metabolism pharmacokinetics pharmacology toxicology

Authors and affiliations

  • G. Gordon Gibson
    • 1
  • Paul Skett
    • 2
  1. 1.University of SurreyUK
  2. 2.University of GlasgowUK

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 1986
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-0-412-26390-3
  • Online ISBN 978-1-4899-3188-7
  • Buy this book on publisher's site