Optical Imaging of Brain Function and Metabolism

  • Ulrich Dirnagl
  • Arno Villringer
  • Karl M. Einhäupl

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 333)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Near Infrared Spectroscopy of the Brain

    1. M. Essenpreis, M. Cope, C. E. Elwell, S. R. Arridge, P. van der Zee, D. T. Delpy
      Pages 9-20
    2. M. Ferrari, R. A. De Blasi, F. Safoue, Q. Wei, G. Zaccanti
      Pages 21-31
    3. P. W. McCormick, M. C. Stewart, G. D. Lewis, J. M. Zabramski
      Pages 33-42
    4. Y. Shinohara, S. Takagi, N. Shinohara, F. Kawaguchi, Y. Itoh, Y. Yamashita et al.
      Pages 43-46
  3. Imaging of Brain Function Using Intrinsic Signals

  4. Thermal Imaging of the Brain

    1. A. M. Gorbach
      Pages 95-123
    2. J. S. George, J. D. Lewine, A. S. Goggin, R. B. Dyer, E. R. Flynn
      Pages 125-136
  5. Optical Measurement of Ion Concentrations in Brain Cells and Tissues

  6. Optical Access to the Brain Microcirculation

  7. Emerging Optical Techniques

  8. Non-Optical Reference Techniques

  9. Back Matter
    Pages 287-296

About this book


• . . . . At last the doctor will be freed from the tedious interpretation of screens and photographs. Instead, he will examine and scan through his patient directly. Wearing optical-shutter spectacles and aiming a pulsed laser torch, he will be able to peer at the beating heart, study the movement of a joint or the flexing of a muscle, press on suspect areas to see how the organs beneath respond, check that pills have been correctly swallowed or that an implant is savely in place, and so on. A patient wearing white cotton or nylon clothes that scatter but hardly absorb light, may not even have to undress . . . . •. David Jones, Nature (1990) 348:290 Optical imaging of the brain is a rapidly growing field of heterogenous techniques that has attracted considerable interest recently due to a number of theoretical advantages in comparison with other brain imaging modalities: it uses non­ ionizing radiation, offers high spatial and temporal resolution, and supplies new types of metabolic and functional information. From a practical standpoint it is important that bedside examinations seem feasible and that the implementations will be considerably less expensive compared with competing techniques. In October 1991, a symposium was held at the Eibsee near Garmisch, Germany to bring together the leading scientists in this new field.


fluorescence imaging infrared spectroscopy magnetic resonance metabolism microscopy neurons optical imaging spectroscopy temperature tissue

Editors and affiliations

  • Ulrich Dirnagl
    • 1
    • 2
  • Arno Villringer
    • 1
  • Karl M. Einhäupl
    • 2
  1. 1.University of MunichMunichGermany
  2. 2.Humboldt UniversityBerlinGermany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1993
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4899-2470-4
  • Online ISBN 978-1-4899-2468-1
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site