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Polymeric Materials in Medication

  • Charles G. Gebelein
  • Charles E. CarraherJr.

Part of the Polymer Science and Technology book series (POLS, volume 32)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Charles G. Gebelein
    Pages 1-9
  3. R. E. Marchant, J. M. Anderson
    Pages 11-26
  4. R. L. Dunn, J. W. Gibson, B. H. Perkins, J. Max Goodson, L. E. Laufe
    Pages 47-59
  5. James L. Gaskill, Pramod P. Sarpotdar, Robert P. Giannini
    Pages 61-71
  6. Y. Raghunathan, L. Amsel, O. Hinsvark, K. Rotenberg
    Pages 73-78
  7. Anna C. Balazs, Daniel F. Calef, J. M. Deutch, Ronald A. Siegel, Robert Langer
    Pages 87-101
  8. Malay Ghosh, Sukumar Maiti
    Pages 103-114
  9. J. L. Alderfer, R. E. Loomis, S. D. Soni, M. Sharma, R. Bernacki, R. Hughes Jr.
    Pages 125-138
  10. J. R. Baldwin, R. A. Carrano, A. R. Imondi, J. D. Iuliucci, L. M. Hagerman
    Pages 139-149
  11. David J. Giron, Mark J. Espy, Charles E. Carraher Jr., Isabel Lopez
    Pages 165-171
  12. Charles E. Carraher Jr., Claredine M. Ademu-John, John J. Fortman, David J. Giron, Carolyn Turner, Raymond Linville
    Pages 173-181
  13. A. Winston, D. V. P. R. Varaprasad, J. J. Metterville, H. Rosenkrantz
    Pages 191-196
  14. C. C. Hinckley, M. A. Islam, P. A. Kibala, J. L. Skosey, D. C. Chow, S. Liu
    Pages 197-210
  15. Ernest M. Hodnett
    Pages 211-226
  16. James M. Samanen
    Pages 227-247
  17. F. Hudecz, H. Votavova, D. Gaal, J. Sponar, J. Kajtar, K. Blaha et al.
    Pages 265-289
  18. Back Matter
    Pages 291-302

About this book

Introduction

The art of using chemical agents for medication dates back into antiquity, although most of the earliest examples used plants, herbs, and other natural materials. The old Egyptian medical papyri, which date from before 1400 B. C. , contain dozens of examples of such medicinal plants and animal extracts. In the Old Testament of the Bible, we can find references to using oil to soften the skin and sores (Isaiah 1:6), the use of tree leaves for medicine (Ezekiel 47:12) and various medical balms (Jeremiah 8:22). Not all these recipes were effective in curing the ailments for which they were used and sometimes the treatment was worse than the disease. Nevertheless, the art of using chemical derived agents for medicines continued to develop and received great impetus during the present century with the rise of synthetic organic chemistry. One of the most vexing problems has always been to achieve specifici­ ty with the medications. While some medical agents do indeed possess a relatively high degree of specificity, most agents are far more systemic than would be desired. Much of the research efforts to correct this deficiency has centered on modifying the chemical agents themselves. Unfortunately, there are severe limitations in this approach since minor modifications often drastically affect the therapeutic activity and can even render the drug completely ineffective, or worse.

Keywords

cancer chemistry drug drug delivery immunomodulation interferon kinetics research toxicity

Editors and affiliations

  • Charles G. Gebelein
    • 1
  • Charles E. CarraherJr.
    • 2
  1. 1.Youngstown State UniversityYoungstownUSA
  2. 2.Florida Atlantic UniversityBoca RatonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4899-2245-8
  • Copyright Information Springer-Verlag US 1985
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4899-2247-2
  • Online ISBN 978-1-4899-2245-8
  • Series Print ISSN 0093-6286
  • Buy this book on publisher's site