© 1996

Models for Assessing Drug Absorption and Metabolism

  • Ronald T. Borchardt
  • Philip L. Smith
  • Glynn Wilson

Part of the Pharmaceutical Biotechnology book series (PBIO, volume 8)

Table of contents

  1. Front Matter
    Pages i-xxii
  2. Ismael J. Hidalgo
    Pages 35-50
  3. Robin Griffiths, Ann Lewis, Phillip Jeffrey
    Pages 67-84
  4. Christopher J. H. Porter, William N. Charman
    Pages 85-102
  5. Elizabeth Quadros, James P. Cassidy, Harry Leipold
    Pages 103-113
  6. M. Vore, Y. Liu, T. C. Ganguly
    Pages 115-120
  7. Edward L. LeCluyse, Peter L. Bullock, Andrew Parkinson, Jerome H. Hochman
    Pages 121-159
  8. Kim L. R. Brouwer, Ronald G. Thurman
    Pages 161-192
  9. Marcelo M. Gutierrez, Claire M. Brett, Kathleen M. Giacomini
    Pages 193-210
  10. Noriko Okudaira, Yuichi Sugiyama
    Pages 211-238
  11. Kenneth L. Audus, Lawrence Ng, Wen Wang, Ronald T. Borchardt
    Pages 239-258
  12. Carla B. Washington, Kathleen M. Giacomini, Claire M. Brett
    Pages 259-283
  13. Patricia M. Reardon
    Pages 309-323
  14. Doris Wall, Doreen Pierdomenico
    Pages 347-359
  15. Mohammed Eljamal, Sudha Nagarajan, John S. Patton
    Pages 361-374

About this book


Pharmaceutical scientists in industry and academia will appreciate this single reference for its detailed experimental procedures for conducting biopharmaceutical studies. This well-illustrated guide allows them to establish, validate, and implement commonly used in situ and in vitro model systems. Chapters provide ready access to these methodologies for studies of the intestinal, buccal, nasal and respiratory, vaginal, ocular, and dermal epithelium as well as the endothelial and elimination barriers.


absorption drug drugs kidney metabolism pharmaceutical research transport

Editors and affiliations

  • Ronald T. Borchardt
    • 1
  • Philip L. Smith
    • 2
  • Glynn Wilson
    • 3
  1. 1.The University of KansasLawrenceUSA
  2. 2.SmithKline Beecham PharmaceuticalsKing of PrussiaUSA
  3. 3.Tacora CorporationSeattleUSA

Bibliographic information

  • Book Title Models for Assessing Drug Absorption and Metabolism
  • Editors Ronald T. Borchardt
    Philip L. Smith
    Glynn Wilson
  • Series Title Pharmaceutical Biotechnology
  • DOI
  • Copyright Information Springer-Verlag US 1996
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-306-45243-7
  • Softcover ISBN 978-1-4899-1865-9
  • eBook ISBN 978-1-4899-1863-5
  • Series ISSN 1078-0467
  • Edition Number 1
  • Number of Pages XXII, 444
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Pharmacology/Toxicology
  • Buy this book on publisher's site