Advertisement

Mammalian Amino Acid Transport

Mechanism and Control

  • Michael S. Kilberg
  • Dieter Häussinger

Table of contents

  1. Front Matter
    Pages i-x
  2. General Aspects

    1. Front Matter
      Pages 1-1
    2. Guido G. Guidotti, Gian C. Gazzola
      Pages 3-29
    3. A. A. Eddy
      Pages 31-49
    4. Rufus M. Williamson, Ti Zhi Su, Dale L. Oxender
      Pages 65-73
    5. Lon J. Van Winkle
      Pages 75-87
    6. Ronald L. Pisoni, Jerry A. Schneider
      Pages 89-99
    7. J. D. McGivan
      Pages 101-112
    8. Dieter Häussinger, Florian Lang, Michael S. Kilberg
      Pages 113-130
  3. Tissue Specific Transport and Functional Implications

    1. Front Matter
      Pages 131-131
    2. Michael S. Kilberg, Dieter Häussinger
      Pages 133-148
    3. Bruce R. Stevens
      Pages 149-163
    4. Quentin R. Smith, Arthur J. L. Cooper
      Pages 165-193
    5. B. Mackenzie, A. Ahmed, M. J. Rennie
      Pages 195-231
    6. J. S. Schwegler, S. Silbernagl, B. K. Tamarappoo, T. C. Welbourne
      Pages 233-260
    7. George B. Segel
      Pages 261-274
    8. Dietrich Keppler, Michael Müller, Toshihisa Ishikawa
      Pages 275-282
    9. Theodorus P. M. Akerboom, Helmut Sies
      Pages 283-294
    10. Halvor N. Christensen
      Pages 295-304
  4. Back Matter
    Pages 305-318

About this book

Introduction

Amino acid transport is a part of each of two larger subjects, amino acid metabolism and the biomembrane transport of various . small molecules and ions. Nevertheless in this volume we treat amino acid transport as more than a fragment of either of these two larger subjects. A more comprehensive approach is justified when we remember two historic and ongoing aspects of the title subject. First, amino acid transport had its beginning and acquired a distinct momentum (even if somewhat interrupted from 1913 until about 1945) as amino acid metabolism with the central and pioneer work of Van Slyke and Meyer in 1913. The reviews in this volume will show that it steadily becomes a larger aspect of amino acid metabolism, broadly perceived. These chapters will show for how many organelles, cells, tissues, organs and organ systems, the transmembrane compartmentations and flows of amino acids play very large parts in their fundamental biological relations. The authors here are tending collectively to evaluate an understanding of amino acid flows across biomernbranes, and the regulation of these flows, as necessary to an ultimate understanding of the full range of development and metabolism. Such an understanding goes far beyond the purely substrate-destabilizing contributions by enzymes, which have often been arbitrarily limited to that conceptual entity, "the cell", and which for so long a splendid time had most of biochemical research attention.

Keywords

Amino acid Biomembran Embryo Mammalia Organe Transporter cell growth cells development enzymes metabolism tissue

Editors and affiliations

  • Michael S. Kilberg
    • 1
  • Dieter Häussinger
    • 2
  1. 1.University of FloridaGainesvilleUSA
  2. 2.Medizinische UniversitätsklinikFreiburg im BreisgauGermany

Bibliographic information