In Vivo Spectroscopy

  • Lawrence J. Berliner
  • Jacques Reuben

Part of the Biological Magnetic Resonance book series (BIMR, volume 11)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Lizann Bolinger, Robert E. Lenkinski
    Pages 1-53
  3. Thomas Schleich, G. Herbert Caines, Jan M. Rydzewski
    Pages 55-134
  4. Lee-Hong Chang, Thomas L. James
    Pages 135-158
  5. Barry S. Selinsky, C. Tyler Burt
    Pages 241-276
  6. Robert E. London
    Pages 277-306
  7. Lawrence J. Berliner, Hirotada Fujii
    Pages 307-319
  8. Back Matter
    Pages 321-334

About this book

Introduction

In vivo nuclear magnetic and electron spin resonance spectroscopy is concerned, inter alia, with the noninvasive observation of metabolic changes in living systems, including animals and humans. Typically, the physiologi­ cal (or pathological) state of an organ or tissue is monitored. This multi­ faceted approach was developed during the 1980s. It is still a research technique, but will undoubtedly become a clinical tool. We are proud to present this volume (the eleventh of our series) in which some of the pioneers in this area summarize their contributions and review related literature. Bolinger and Lenkinski describe a variety of localization methods suitable for clinical applications of NMR spectroscopy. Schleich, Caines, and Rydzewski summarize their contributions to approaches involving off-resonance rotating frame relaxation and critically compare these with other NMR techniques that may yield similar information. Chang and James outline their approach and share their experience with the technical aspects 1 31 of H and P NMR spectroscopy and spatially localized spectroscopy in studies of brain ischemia. Sodium plays an important role in living systems, a key aspect being the large gradient between intra- and extracellular concentrations of sodium that is maintained by a variety of transport mechanisms. Miller and Elgavish give us a comprehensive review of an important research tool in this 23 area- Na NMR spectroscopy as aided by shift reagents.

Keywords

cells magnetic resonance metabolism spectroscopy tissue

Editors and affiliations

  • Lawrence J. Berliner
    • 1
  • Jacques Reuben
    • 2
  1. 1.Department of ChemistryThe Ohio State UniversityColumbusUSA
  2. 2.Research CenterHercules IncorporatedWilmingtonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4757-9477-9
  • Copyright Information Springer-Verlag US 1992
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4757-9479-3
  • Online ISBN 978-1-4757-9477-9
  • Series Print ISSN 0192-6020
  • About this book