Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular

  • Eric Reid
  • J. D. Robinson
  • Ian D. Wilson

Part of the Methodological Surveys in Biochemistry and Analysis book series (MSBA, volume 18 A)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Eicosanoids and Related Analytes

    1. Front Matter
      Pages 1-1
    2. J. C. Frölich, K.-H. Marx, H. Bippi, J. Fauler, B. Rosenkranz, U. Förstermann
      Pages 15-21
    3. Claudia Weber, Klaus Belsner, Barbara Osikowska-Evers, Inge Luhmann, Michael Höller
      Pages 23-27
    4. L. A. Allan, A. J. Hawkins, J. Firth, R. D. Brownsill, J. A. Steiner, C. W. Vose
      Pages 29-35
    5. Joachim Fauler, Karl-Heinz Marx, Volkhard Kaever
      Pages 37-41
  3. Notes and Comments Relating to Eicosanoids and Related Analytes

  4. Anti-Inflammatory Drugs

  5. Notes and Comments Relating to Anti-Inflammatory Drugs

    1. Front Matter
      Pages 127-127
    2. C. J. Dyde, M. F. Barkworth, K. D. Rehm
      Pages 129-132
  6. ACE Inhibitors and Calcium Antagonists

    1. Front Matter
      Pages 133-133
    2. J. D. Robinson, S. Lewis
      Pages 143-148
    3. Robert Woestenborghs, Philip Timmerman, Achiel Van Peer, Jos Heykants
      Pages 149-155
  7. Notes and Comments Relating to ACE Inhibitors and Calcium Antagonists

    1. Front Matter
      Pages 157-157
    2. Peter S. B. Minty, Felicity A. Tucker
      Pages 159-161
  8. Various Cardiovascular Drugs

    1. Front Matter
      Pages 167-167
    2. Richard L. Lalonde, Michael B. Bottorff, Irving W. Wainer
      Pages 169-177
    3. B. J. Starkey, A. J. E. Green, G. P. Mould
      Pages 185-191
    4. P. H. Degen
      Pages 193-200
    5. R. D. McDowall, J. C. Pearce, G. S. Murkitt, J. A. Jelly, W. J. Leavens, K. A. Fernandes et al.
      Pages 201-206
  9. Notes and Comments Relating to Various Cardiovascular Drugs

    1. Front Matter
      Pages 207-207
    2. Stephen H. Curry, Hae-Ryun Kwon
      Pages 213-214
  10. Various Drugs and Separatory Approaches

    1. Front Matter
      Pages 223-223
    2. John G. Dorsey
      Pages 235-244
    3. A. J. Woodward, P. A. Lewis, J. Maddock, D. Donnell
      Pages 245-250
    4. D. J. K. van der Stel, O. A. M. Brockhoff, H. de Bree
      Pages 251-255
    5. John Caldwell, John F. Derbyshire, Steven M. Winter, Andrew J. Hutt
      Pages 257-261
  11. Notes and Comments Relating to Various Drugs and Separatory Approaches

About this book


vi as did non-appreciation that % values for bought-in solutions (notably ammonia) may be on a weight basis, not made evident by the manufacturer. Notwithstanding the shortcomings or lateness of some texts, authors are thanked for compiling them amidst other pressures. Elsevier and the American Chemical Society are also thanked, for Figures now reproduced with source acknowledgement. This Editor has generally respected authors' phrasing, whilst shuddering when the term 'incubate' is encountered in a 0° context. He remains a 'diehard' in certain respects, notably in favouring 'M' rather than 'mol/I', and a wt./ml basis for drug concentrations in test samples; he regards 'mmol/l' as a fatuous fashion. Concerning infelicitous abbreviations, a distinction is made between electron­ capture (detector context; 'ECD') and electrochemical ('EC', never 'ECD'); the hallowed GC term 'FID' means free induction decay to NMR practi tione:ts, who may pardon the term 'Fid' as introduced editorially. The convention for ,0C' throughout the book is '0'. Undefined but well-known abbreviations include GC, HPLC and TLC. MS (mass spectrometry), NPD (nitrogen-phosphorus detector), tr (retention time) and RIA (radioimmunoassay) are usually defined in the article concerned, as are the HPLC modes NP (normal-/straight­ phase) and RP (reversed-phase; C-lS and ODS are synonymous), and i.s.


Mass Spectrometry NMR drug nitrogen nuclear magnetic resonance (NMR) phase phosphorus research society spectrometry

Editors and affiliations

  • Eric Reid
    • 1
  • J. D. Robinson
    • 2
  • Ian D. Wilson
    • 3
  1. 1.Guildford Academic AssociatesGuildfordUK
  2. 2.Hoechst UKMilton KeynesUK
  3. 3.ICI Pharmaceuticals DivisionMacclesfieldUK

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 1988
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4757-9426-7
  • Online ISBN 978-1-4757-9424-3
  • Buy this book on publisher's site