Clinical Research in Diabetes and Obesity

Diabetes and Obesity

  • Boris Draznin
  • Robert Rizza

Part of the Contemporary Biomedicine book series (CB, volume 15)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Obesity

    1. Front Matter
      Pages 1-1
    2. James O. Hill
      Pages 3-12
    3. Michael W. Schwartz, Denis G. Baskin, Karl J. Kaiyala, Steven C. Woods, Daniel Porte Jr.
      Pages 25-56
    4. David E. Kelley, Jean-Aime Simoneau
      Pages 57-72
    5. Ahmed H. Kissebah, Glenn R. Krakower
      Pages 73-91
  3. Noninsulin-Dependent Diabetes Mellitus

    1. Front Matter
      Pages 93-93
    2. Henning Beck-Nielsen, Allan Vaag, Kirsten Ohm Kyvik
      Pages 95-117
    3. Yogish C. Kudva, Peter C. Butler
      Pages 119-136
    4. Lisa A. Kosmiski, Robert H. Eckel
      Pages 159-185
    5. Judith G. Regensteiner, Suzanne L. Brandenburg, Jane E. B. Reusch
      Pages 187-201
    6. Hannele Yki-Järvinen
      Pages 203-218
    7. Alain D. Baron, Helmut O. Steinberg
      Pages 233-246
  4. Insights Gained from Other Insulin-Resistance Syndromes

    1. Front Matter
      Pages 247-247
    2. Andrea Dunaif, Carol Beth Book
      Pages 249-274
    3. Frank Q. Nuttall, Mary C. Gannon
      Pages 275-299
    4. Andrea Natali, Stefano Taddei, Ele Ferrannini
      Pages 301-322
    5. Gerald M. Reaven
      Pages 357-382
  5. Back Matter
    Pages 383-392

About this book


In Clinical Research in Diabetes and Obesity premier clinical scientists around the world offer an unprecedented compilation of state-of-the-art advances in clinical research on diabetes and obesity. This second volume, on Diabetes and Obesity, discusses the methods of clinical research and the interpretation of their results in studies of normal individuals, obese subjects, and patients with diabetes mellitus. Along the way, the authoritative contributors writing here illuminate how changes in the hormone action and substrate metabolism of healthy humans may lead to obesity and noninsulin-dependent diabetes mellitus. A first volume, Methods, Assessment, and Metabolic Regulation, provides the methodological basis for the present work by presenting and critically assessing the major techniques used in clinical research, as well as reviewing their use in studying healthy humans.

Clinical Research in Diabetes and Obesity presents in its two wide-ranging volumes not only all of today's cutting-edge in vivo techniques, but also details approaches to elucidating the pathophysiology of these diseases, and sheds light on the latest therapeutic modalities. Its comprehensive overview of the regulation of carbohydrate, protein, and lipid metabolism in diabetic and nondiabetic humans will prove an especially valuable contribution both to the clinical science and to the care of people suffering from obesity and diabetes.


Diabetes Diabetes mellitus Insulin Insulin Secretion genetics insulin resistance

Editors and affiliations

  • Boris Draznin
    • 1
  • Robert Rizza
    • 2
  1. 1.Veteran’s Affairs Medical CenterDenverUSA
  2. 2.Mayo ClinicRochesterUSA

Bibliographic information