Hormone Signaling

  • Vincent Goffin
  • Paul A. Kelly

Part of the Endocrine Updates book series (ENDO, volume 17)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Fundamental Mechanisms in Signaling

    1. Front Matter
      Pages 1-1
    2. Vincent Goffin, Paul A. Kelly
      Pages 3-19
    3. Yu Zhao, Zhong-Yin Zhang
      Pages 21-36
    4. Véronique Volmat, Jacques Pouysségur
      Pages 37-53
  3. Receptor Tyrosine Kinases

    1. Front Matter
      Pages 55-55
    2. Alan Wells
      Pages 57-79
  4. Cytokine Receptors

    1. Front Matter
      Pages 101-101
    2. Warren J. Leonard
      Pages 103-120
    3. Li-yuan Yu-Lee, Sébastien Jeay
      Pages 121-143
    4. Fabrice Gouilleux
      Pages 145-178
  5. G Protein-Coupled Receptors

    1. Front Matter
      Pages 179-179
    2. Michael A. Shetzline, Marc G. Caron
      Pages 181-197
    3. Nicolas de Roux, Beate Doeker, Edwin Milgrom
      Pages 199-219
    4. Gastone G. Nussdorfer, Gian Paolo Rossi
      Pages 221-237
  6. Nuclear Receptors

    1. Front Matter
      Pages 239-239
    2. William Bourguet, Pierre Germain, Hinrich Gronemeyer
      Pages 241-267
    3. Zhang Weihua, Guojun Cheng, Ling Wang, Hideki Sakaguchi, Margaret Warner, Jan-Åke Gustafsson
      Pages 269-282
    4. Béatrice Desvergne, Liliane Michalik, Walter Wahli
      Pages 283-304
  7. Back Matter
    Pages 305-314

About this book


Multicellular organisms require a means of intracellular communication to organize and develop the complex body plan that occurs during embryogenesis and then for cell and organ systems to access and respond to an ever changing environmental milieu. Mediators of this constant exchange of information are growth factors, neurotransmmitters, peptide and protein hormones which bind to cell surface receptors and transduce their signals from the extracellular space to the intracellular compartment. Via multiple signaling pathways, receptors of this general class affect growth, development and differentiation. Smaller hydrophobic signaling molecules, such as steroids and non-steroid hormones, vitamins and metabolic mediators interact with a large family of nuclear receptors. These receptors function as transcription factors affecting gene expression, to regulate the multiple aspects of animal and human physiology, including development, reproduction and homeostasis.
The aim of this book is to cover various aspects of intracellular signaling involving hormone receptors.


EGF receptor G protein-coupled receptors TSH receptors cytokine receptors erythropoietin estrogen action estrogen receptor growth hormone receptors insulin leptin receptors metabolic control protein phosphorylation signaling system spatio-temporal parameters thrombopoietin

Editors and affiliations

  • Vincent Goffin
    • 1
  • Paul A. Kelly
    • 1
  1. 1.Inserm Unit 344, Molecular EndocrinologyFaculty of Medicine NeckerParisFrance

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 2002
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4419-4948-6
  • Online ISBN 978-1-4757-3600-7
  • Series Print ISSN 1566-0729
  • Buy this book on publisher's site