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Targeted Molecular Imaging in Oncology

  • E. Edmund Kim
  • David J. Yang

Table of contents

  1. Front Matter
    Pages i-xvi
  2. E. Edmund Kim, David J. Yang
    Pages 1-13
  3. David J. Yang, Tomio Inoue, E. Edmund Kim
    Pages 62-82
  4. Noboru Oriuchi, David J. Yang
    Pages 83-87
  5. E. Edmund Kim
    Pages 88-101
  6. Franklin C. L. Wong, E. Edmund Kim
    Pages 102-110
  7. Chun Li, Edward F. Jackson
    Pages 111-120
  8. E. Edmund Kim, Franklin C. L. Wong
    Pages 121-133
  9. E. Edmund Kim, Franklin C. L. Wong
    Pages 134-154
  10. E. Edmund Kim
    Pages 164-171
  11. E. Edmund Kim
    Pages 172-178
  12. David J. Yang, Chun Li, E. Edmund Kim
    Pages 185-199
  13. Kenneth C. Wright, E. Edmund Kim
    Pages 200-214
  14. David J. Yang, E. Edmund Kim
    Pages 215-228
  15. David J. Yang, E. Edmund Kim
    Pages 229-244
  16. Carolyn Nichol, E. Edmund Kim
    Pages 245-259
  17. Zuxing Kan, E. Edmund Kim
    Pages 260-271
  18. Back Matter
    Pages 273-289

About this book

Introduction

Cancer cells dedifferentiate with repect to cell function; their vascularity is more leaky, but perfusion is heterogenerously reduced, and interstitial fluid pressure is high, severely retarding delivery of agents from the blood. Targeted imaging is designed to produce a detectable difference between tissue that is visualized with single photon and positron emission tomography, magnetic resonance imaging, computed tomography, or ultrasonography. This book uniquely reports strategies for the application of molecular targeted imaging agents such as antibodies, peptides, receptors and contrast agents in the biologic grading of tumors, differential diagnosis of tumors, prediction of therapeutic response and monitoring tumor response to treatment. This book also describes updated information about the imaging of tumor angiogenesis, hypoxia, apoptosis and gene delivery as well as expression in the understanding and utility of tumor molecular biology for better cancer management.

Keywords

Grading Tumor angiogenesis apoptosis cancer computed tomography computed tomography (CT) diagnosis imaging magnetic resonance magnetic resonance imaging (MRI) molecular biology molecular imaging positron emission tomography (PET) tomography

Editors and affiliations

  • E. Edmund Kim
    • 1
  • David J. Yang
    • 1
  1. 1.Departments of Nuclear Medicine and Diagnostic RadiologyThe University of Texas M.D. Anderson Cancer CenterHoustonUSA

Bibliographic information